ArticleProceedings of the National Academy of Sciences of the United States of America2012
Reshaping of the maize transcriptome by domestication.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.
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81 citing papers in PubMed.
- A domestication-selected CIPK-MYB-HAK module improves salt tolerance in modern maize.Nature plants · 2026Article
- Regulatory divergence of homoeologs underlies network optimization for fiber improvement in domesticated cotton.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Network Properties Influence Covariance Between Gene Expression and Fecundity Fitness of Caenorhabditis elegans in a Novel Laboratory Environment.Genome biology and evolution · 2026Article
- An allelic resolution gene atlas for tetraploid potato provides insights into tuberization and stress resilience.The Plant journal : for cell and molecular biology · 2025Article
- Enhancing local meiotic crossovers in Arabidopsis and maize through juxtaposition of heterozygous and homozygous regions.Nature plants · 2025Article
- The origins and spread of the opium poppy (Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Article
- A new approach for evaluating maize transgressive segregants and their three-way cross potential in the S4 convergent breeding population.BMC plant biology · 2025Article
- Transcriptomic response to nitrogen availability reveals signatures of adaptive plasticity during tetraploid wheat domestication.The Plant cell · 2024Article
- Gene expression and alternative splicing contribute to adaptive divergence of ecotypes.Heredity · 2024Article
- Article
- ZmEREB92 plays a negative role in seed germination by regulating ethylene signaling and starch mobilization in maize.PLoS genetics · 2023Article
- Fluctuation of ecological niches and geographic range shifts along chile pepper's domestication gradient.Ecology and evolution · 2023Article
- Domestication over Speciation in Allopolyploid Cotton Species: A Stronger Transcriptomic Pull.Genes · 2023Article
- Mining genes regulating root system architecture in maize based on data integration analysis.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- A role for heritable transcriptomic variation in maize adaptation to temperate environments.Genome biology · 2023Article
- A teosinte-derived allele of an HKT1 family sodium transporter improves salt tolerance in maize.Plant biotechnology journal · 2023Article
- Combined population transcriptomic and genomic analysis reveals cis-regulatory differentiation of non-coding RNAs in maize.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Article
- Comparative transcriptomics of wild and commercial Citrus during early ripening reveals how domestication shaped fruit gene expression.BMC plant biology · 2022Article
- Gene network simulations provide testable predictions for the molecular domestication syndrome.Genetics · 2022Article
21 more citing papers are in PubMed but not listed here.
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8 authors.
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Abstract
Through domestication, humans have substantially altered the morphology of Zea mays ssp. parviglumis (teosinte) into the currently recognizable maize. This system serves as a model for studying adaptation, genome evolution, and the genetics and evolution of complex traits. To examine how domestication has reshaped the transcriptome of maize seedlings, we used expression profiling of 18,242 genes for 38 diverse maize genotypes and 24 teosinte genotypes. We detected evidence for more than 600 genes having significantly different expression levels in maize compared with teosinte. Moreover, more than 1,100 genes showed significantly altered coexpression profiles, reflective of substantial rewiring of the transcriptome since domestication. The genes with altered expression show a significant enrichment for genes previously identified through population genetic analyses as likely targets of selection during maize domestication and improvement; 46 genes previously identified as putative targets of selection also exhibit altered expression levels and coexpression relationships. We also identified 45 genes with altered, primarily higher, expression in inbred relative to outcrossed teosinte. These genes are enriched for functions related to biotic stress and may reflect responses to the effects of inbreeding. This study not only documents alterations in the maize transcriptome following domestication, identifying several genes that may have contributed to the evolution of maize, but highlights the complementary information that can be gained by combining gene expression with population genetic analyses.
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