ArticleThe Journal of biological chemistry2012
Proteomic analysis of α-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor complexes.
Article in The Journal of biological chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- LARGE protein drives activity-induced homeostatic resetting.Science advances · 2025Article
- Proteomic insights into synaptic signaling in the brain: the past, present and future.Molecular brain · 2021Review
- AMPA receptor structure and auxiliary subunits.The Journal of physiology · 2021Review
- Roles of the DOCK-D family proteins in a mouse model of neuroinflammation.The Journal of biological chemistry · 2020Article
- LARGE, an intellectual disability-associated protein, regulates AMPA-type glutamate receptor trafficking and memory.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- SPARC and GluA1-Containing AMPA Receptors Promote Neuronal Health Following CNS Injury.Frontiers in cellular neuroscience · 2018Article
- Proteomic Analysis of Postsynaptic Protein Complexes Underlying Neuronal Plasticity.ACS chemical neuroscience · 2017Review
- Subunit-specific synaptic delivery of AMPA receptors by auxiliary chaperone proteins TARPγ8 and GSG1L in classical conditioning.Neuroscience letters · 2017Article
- Chronic intermittent alcohol disrupts the GluN2B-associated proteome and specifically regulates group I mGlu receptor-dependent long-term depression.Addiction biology · 2017Article
- Differential Alteration in Expression of Striatal GABAFrontiers in molecular neuroscience · 2017Article
- SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion.Nature communications · 2016Article
- Regulation of AMPA receptor subunit GluA1 surface expression by PAK3 phosphorylation.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- FXR1P limits long-term memory, long-lasting synaptic potentiation, and de novo GluA2 translation.Cell reports · 2014Article
- Molecular dissection of the interaction between the AMPA receptor and cornichon homolog-3.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- RHO to the DOCK for GDP disembarking: Structural insights into the DOCK GTPase nucleotide exchange factors.The Journal of biological chemistryReview
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Authors and funding
6 authors.
Funding
Abstract
The AMPA receptor (AMPA-R) is a major excitatory neurotransmitter receptor in the brain. Identifying and characterizing the neuronal proteins interacting with AMPA-Rs have provided important information about the molecular mechanisms underlying synaptic transmission and plasticity. In this study, to identify more AMPA-R interactors in vivo, we performed proteomic analyses of AMPA-R complexes from the brain. AMPA-R complexes were isolated from the brain through various combinations of biochemical techniques for solubilization, enrichment, and immunoprecipitation. Mass spectrometry analyses of these isolated complexes identified several novel components of the AMPA-R complexes as well as some previously identified components. The identification of these novel components helps to further define the complex mechanisms involved in the regulation of AMPA receptor function and synaptic plasticity.
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