ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2013
The use of fibrin matrix-mixed gel-type autologous chondrocyte implantation in the treatment for osteochondral lesions of the talus.
Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Clinical Applicability of Autologous Chondrocyte Implantation for the Treatment of Osteochondral Defects: A Meta-analysis.Current rheumatology reviews · 2024Pooled it
- Pooled it
- No superior treatment for primary osteochondral defects of the talus.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2018Pooled it
- No superior surgical treatment for secondary osteochondral defects of the talus.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2018Pooled it
- Medial Malleolus Triple-Plane Osteotomy With Autologous Iliac Bone Grafting for the Treatment of Talar Cysts.Orthopaedic surgery · 2026Article
- Acute on chronic stress fracture after a medial malleolar osteotomy following osteochondral lesion of the talus treatment.BMJ case reports · 2025Article
- Comparative study of arthroscopic autologous cancellous bone grafting and medial malleolar osteotomy combined with autologous periosteal iliac bone grafting for the treatment of osteochondral lesions of the talus.Journal of orthopaedic surgery and research · 2025Article
- Gel-Based Autologous Chondrocyte Implantation (GACI) in the Chondral Defects of the Knee: An Observational Study.Indian journal of orthopaedics · 2023Article
- Medial oblique malleolar osteotomy for approach of medial osteochondral lesion of the talus.Archives of orthopaedic and trauma surgery · 2023Article
- Correlation of Postoperative Imaging With MRI and Clinical Outcome After Cartilage Repair of the Ankle: A Systematic Review and Meta-analysis.Foot & ankle orthopaedics · 2022Article
- Cell therapy for cartilage repair.Emerging topics in life sciences · 2021Review
- AMIC for traumatic focal osteochondral defect of the talar shoulder: a 5 years follow-up prospective cohort study.BMC musculoskeletal disorders · 2021Article
- Outcomes of arthroscopic bone graft transplantation for Hepple stage V osteochondral lesions of the talus.Annals of translational medicine · 2021Article
- Talar OsteoPeriostic grafting from the Iliac Crest (TOPIC) for large medial talar osteochondral defects : Operative technique.Operative Orthopadie und Traumatologie · 2021Article
- Autologous Matrix Induced Chondrogenesis (AMIC) Compared to Microfractures for Chondral Defects of the Talar Shoulder: A Five-Year Follow-Up Prospective Cohort Study.Life (Basel, Switzerland) · 2021Article
- Open reconstruction with autologous spongiosa grafts and matrix-induced chondrogenesis for osteochondral lesions of the talus can be performed without medial malleolar osteotomy.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2019Article
- Scaffolds based therapy for osteochondral lesions of the talus: A systematic review.World journal of orthopedics · 2017Article
- Medial malleolar osteotomy for the treatment of talar osteochondral lesions: anatomical and morbidity considerations.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2016Article
- [Malleolar osteotomy--osteotomy as approach].Der Orthopade · 2013Article
- Diagnosis and treatment of osteochondral lesions of the ankle: current concepts.Revista brasileira de ortopediaReview
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study assessed the clinical results and second-look arthroscopy after fibrin matrix-mixed gel-type autologous chondrocyte implantation to treat osteochondral lesions of the talus.
methodsChondrocytes were harvested from the cuboid surface of the calcaneus in 38 patients and cultured, and gel-type autologous chondrocyte implantation was performed with or without medial malleolar osteotomy. Preoperative American orthopedic foot and ankle society ankle-hind foot scores, visual analogue score, Hannover scoring system and subjective satisfaction were investigated, and the comparison of arthroscopic results (36/38, 94.7 %) and MRI investigation of chondral recovery was performed. Direct tenderness and relationship to the active daily life of the donor site was evaluated.
resultsThe preoperative mean ankle-hind foot scores (71 ± 14) and Hannover scoring system (65 ± 10) had increased to 91 ± 12 and 93 ± 14, respectively, at 24-month follow-up (p < 0.0001), and the preoperative visual analogue score of 58 mm had decreased to 21 mm (p < 0.0001). Regarding subjective satisfaction, 34 cases (89.5 %) reported excellent, good or fair. Chondral regeneration was analysed by second-look arthroscopy and MRI. Complications included one non-union and two delayed-unions of the osteotomy sites, and 9 ankles (9/31, 29.0 %) sustained damaged medial malleolar cartilage due to osteotomy. Marked symptoms at the biopsy site did not adversely affect the patient's active daily life.
conclusionsFibrin matrix-mixed gel-type autologous chondrocyte implantation using the cuboid surface of the calcaneus as a donor can be used for treating osteochondral lesions of the talus.
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