Evidence map›Paper›PMID 22752406›Full record

ArticleEuropean radiology2012

Description and validation of a scoring system for tomosynthesis in pulmonary cystic fibrosis.

Kristina Vult von Steyern, Isabella M Björkman-Burtscher, Peter Höglund, Gracijela Bozovic, Marie Wiklund, Mats Geijer

Abstract readValidation Study
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Article in European radiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

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17citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Kristina Vult von SteyernCentre for Medical Imaging and Physiology, Skåne University Hospital, Lund University, 221 85, Lund, Sweden. kristina.vult_von_steyern@med.lu.se
Isabella M Björkman-Burtscher
Peter Höglund
Gracijela Bozovic
Marie Wiklund
Mats Geijer

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo design and validate a scoring system for tomosynthesis (digital tomography) in pulmonary cystic fibrosis.

methodsA scoring system dedicated to tomosynthesis in pulmonary cystic fibrosis was designed. Three radiologists independently scored 88 pairs of radiographs and tomosynthesis examinations of the chest in 60 patients with cystic fibrosis and 7 oncology patients. Radiographs were scored according to the Brasfield scoring system and tomosynthesis examinations were scored using the new scoring system.

resultsObserver agreements for the tomosynthesis score were almost perfect for the total score with square-weighted kappa >0.90, and generally substantial to almost perfect for subscores. Correlation between the tomosynthesis score and the Brasfield score was good for the three observers (Kendall's rank correlation tau 0.68, 0.77 and 0.78). Tomosynthesis was generally scored higher as a percentage of the maximum score. Observer agreements for the total score for Brasfield score were almost perfect (square-weighted kappa 0.80, 0.81 and 0.85).

conclusionsThe tomosynthesis scoring system seems robust and correlates well with the Brasfield score. Compared with radiography, tomosynthesis is more sensitive to cystic fibrosis changes, especially bronchiectasis and mucus plugging, and the new tomosynthesis scoring system offers the possibility of more detailed and accurate scoring of disease severity. KEY POINTS: Tomosynthesis is more sensitive than conventional radiography for pulmonary cystic fibrosis changes. The radiation dose from chest tomosynthesis is low compared with computed tomography. Tomosynthesis may become useful in the regular follow-up of patients with cystic fibrosis.

Indexed as

Severity of Illness IndexAdolescentAdultChildCystic FibrosisFemaleHumansMaleMiddle AgedProspective StudiesRadiography, ThoracicTomography, X-Ray Computed

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.