Evidence map›Paper›PMID 22752233›Full record

ArticleArchives of general psychiatry2012

Effects of Medicare Part D coverage gap on medication and medical treatment among elderly beneficiaries with depression.

Yuting Zhang, Seo Hyon Baik, Lei Zhou, Charles F Reynolds, Judith R Lave

Open access · bronzeAbstract read
In one paragraph

Article in Archives of general psychiatry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pharmaceutical policies: effects of financial incentives for prescribers.The Cochrane database of systematic reviews · 2015
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yuting ZhangDepartment of Health Policy and Management, Graduate School of Public Health, University of Pittsburgh, Pennsylvania, USA.
Seo Hyon Baik
Lei Zhou
Charles F Reynolds
Judith R Lave
University of Pittsburgh · US

Funding

UNIVERSITY OF PITTSBURGH CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE: BPCAUL1RR024153 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$73.9M
University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
RESEARCH METHODS COREP30MH090333 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DEW, MARY AMANDA · 2011 to 2015
$8.3M
Comparing Methods to Pay for Psychotropic Medications for Medicare BeneficiariesRC1MH088510 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ZHANG, YUTING · 2009 to 2010
$912k
Racial and Ethnic Differences in Response to the Medicare Coverage Gap among PatiR01HS018657 · AHRQ · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ZHANG, YUTING · 2010 to 2012
$676k
AHRQ HHS R01 HS018657NCATS NIH HHS UL1 TR000005NCRR NIH HHS UL1 RR024153NIMH NIH HHS P30 MH090333NIMH NIH HHS RC1 MH088510NIMH NIH HHS RC1MH088510
6 · The paper itself

Abstract

contextMaintenance antidepressant pharmacotherapy in late life prevents recurrent episodes of major depression. The coverage gap in Medicare Part D could increase the likelihood of reducing appropriate use of antidepressants, thereby exposing older adults to an increased risk for relapse of depressive episodes.

objectivesTo determine whether (1) beneficiaries reduce antidepressant use in the gap, (2) the reduction in antidepressant use is similar to the reduction in heart failure medications and antidiabetics, (3) the provision of generic coverage reduces the risk of reduction of medication use, and (4) medical spending increases in the gap.

designObservational before-after study with a comparison group design. SETTING AND PATIENTS: A 5% random sample of US Medicare beneficiaries 65 years or older with depression (n = 65,223) enrolled in stand-alone Part D plans in 2007.

main outcome measuresAntidepressant pharmacotherapy, physician, outpatient, and inpatient spending.

resultsBeing in the gap was associated with comparable reductions in the use of antidepressants, heart failure medications, and antidiabetics. Relative to the comparison group (those who had full coverage in the gap because of Medicare coverage or low-income subsidies), the no-coverage group reduced their monthly antidepressant prescriptions by 12.1% (95% CI, 9.9%-14.3%) from the pregap level, whereas they reduced use of heart failure drugs and antidiabetics by 12.9% and 13.4%, respectively. Those with generic drug coverage in the gap reduced their monthly antidepressant prescriptions by 6.9% (95% CI, 4.8%-9.1%); this decrease was entirely attributable to the reduction in the use of brand-name antidepressants. Medicare spending on medical care did not increase for either group relative to the comparison group.

conclusionsThe Medicare Part D coverage gap was associated with modest reductions in the use of antidepressants. Those with generic coverage reduced their use of brand-name drugs and did not switch from brand-name to generic drugs. The reduction in antidepressant use was not associated with an increase in nondrug medical spending.

Indexed as

AgedAged, 80 and overAntidepressive AgentsDepressive DisorderDrug UtilizationFemaleHealth Services AccessibilityHumansInsurance CoverageMaleMedicare Part DUnited StatesAntidepressive Agents

Identifiers

PMID22752233
PMCPMC3390754
OpenAlexW1996298725

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.