Evidence map›Paper›PMID 22752068›Full record

Trial reportThe oncologist2012

Safety of weightlifting among women with or at risk for breast cancer-related lymphedema: musculoskeletal injuries and health care use in a weightlifting rehabilitation trial.

Justin C Brown, Andrea B Troxel, Kathryn H Schmitz

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The oncologist, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Effects of resistance training on breast cancer-related arm lymphedema: a systematic review and dose-response meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  2. Resistance Training in Breast Cancer Survivors: A Systematic Review of Exercise Programs.International journal of environmental research and public health · 2020
    Pooled it
  3. Pooled it
  4. Physical activity for women with breast cancer after adjuvant therapy.The Cochrane database of systematic reviews · 2018
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Survivorship: healthy lifestyles, version 2.2014.Journal of the National Comprehensive Cancer Network : JNCCN · 2014
    Guideline
  8. Trial
  9. Trial
  10. Weight Lifting and Physical Function Among Survivors of Breast Cancer: A Post Hoc Analysis of a Randomized Controlled Trial.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2015
    Trial
  11. Trial
  12. Trial
  13. Prescription and adherence to lymphedema self-care modalities among women with breast cancer-related lymphedema.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2014
    Trial
  14. Trial
  15. Article
  16. Article
  17. Review
  18. Survivorship, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.Journal of the National Comprehensive Cancer Network : JNCCN · 2018
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Justin C BrownDepartment of Biostatistics and Epidemiology and Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Andrea B Troxel
Kathryn H Schmitz

Funding

Physical Activity and Lymphedema Project (PAL Trial)R01CA106851 · NCI · UNIVERSITY OF PENNSYLVANIA · PI SCHMITZ, KATHRYN H. · 2004 to 2007
$2.2M
NCI NIH HHS R01 CA106851
6 · The paper itself

Abstract

introductionIt has been noted that only 14% of all clinical trials are translated into practice. The objective of this paper is to promote translation of an efficacious rehabilitative exercise program for breast cancer survivors by clarifying for clinicians the safety profile of participants (e.g., rates of musculoskeletal injury and referral to medical professionals), and to use this evidence to make recommendations on the appropriate training of health and fitness staff who would be capable of safely, effectively, and sustainably delivering the program.

methodsBreast cancer survivors with and at risk for lymphedema were randomized to twice-weekly weightlifting or standard care for 1 year. An injury survey and health care evaluation were administered after 1 year and in 3-month intervals, respectively.

resultsThe cumulative incidence and rate of injury were higher in the weightlifting than in the control group. The injury rates were 2.3 and 0.3 per 1,000 bouts of weightlifting among breast cancer survivors with and at risk for lymphedema, respectively. Among breast cancer survivors with or at risk for lymphedema, 20.9% in the weightlifting group had an encounter with a health care provider that required cessation or dose modification of weightlifting.

conclusionDespite the demonstrated efficacy of weightlifting, musculoskeletal injuries and other health problems did occur. Therefore, for the successful translation of this rehabilitative intervention into clinical practice, health and fitness professionals working with breast cancer survivors need the knowledge, skills, and abilities that clarify their scope of practice to address these health care needs.

Indexed as

Breast NeoplasmsLymphedemaAdultAthletic InjuriesFemaleHumansMusculoskeletal SystemResistance TrainingRiskSurvivors

Identifiers

PMID22752068
PMCPMC3425531

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.