p53-dependent growth arrest and induction of p21: a critical role for PCAF-mediated histone acetylation.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

1. Targeting the p53 signaling pathway in cancers: Molecular mechanisms and clinical studies.MedComm · 2023
   Review
2. Metformin Induces Apoptosis in Human Pancreatic Cancer (PC) Cells Accompanied by Changes in the Levels of Histone Acetyltransferases (Particularly, p300/CBP-Associated Factor (PCAF) Protein Levels).Pharmaceuticals (Basel, Switzerland) · 2023
   Article
3. Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.Medical science monitor : international medical journal of experimental and clinical research · 2021
   Article
4. Polysaccharide from Angelica sinensis attenuates SNP-induced apoptosis in osteoarthritis chondrocytes by inducing autophagy via the ERK1/2 pathway.Arthritis research & therapy · 2021
   Article
5. PSMC2 Regulates Cell Cycle Progression Through the p21/Cyclin D1 Pathway and Predicts a Poor Prognosis in Human Hepatocellular Carcinoma.Frontiers in oncology · 2021
   Article
6. lncRNAAging · 2019
   Article
7. Loss of BRG1 induces CRC cell senescence by regulating p53/p21 pathway.Cell death & disease · 2017
   Article
8. PCAF-mediated Akt1 acetylation enhances the proliferation of human glioblastoma cells.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015
   Article
9. GCN5 inhibits XBP-1S-mediated transcription by antagonizing PCAF action.Oncotarget · 2015
   Article
10. Radiosensitization by histone deacetylase inhibition in an osteosarcoma mouse model.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2013
    Article
11. Molecular dynamics of the full-length p53 monomer.Cell cycle (Georgetown, Tex.) · 2013
    Article

Corrections and comments

• Comment on
  The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3.2012

Authors and funding

1 author at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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