ArticleJournal of biomedical informatics2012
Cross-terminology mapping challenges: a demonstration using medication terminological systems.
Article in Journal of biomedical informatics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Representing Traditional East Asian Medicine in International Health Informatics Standards: A Scoping Review.Healthcare (Basel, Switzerland) · 2026Review
- Psychotropic prescription trends in jails from 2013 to 2023: findings from the REACH database.Scientific reports · 2025Article
- Development and evaluation of a patient-centric approach for accurate medication capture.JAMIA open · 2025Article
- Semiautomatic mapping of a national drug terminology to standardised OMOP drug concepts using publicly available supplementary information.BMC medical research methodology · 2025Article
- Methods and Observations from Routinely Collected Electronic Health Record Data in a Nationwide Jail Population: Introducing the Registry of Electronic Archives in Correctional Healthcare (REACH) Database.Health & justice · 2025Article
- A call to action for adverse drug event (ADE) detection and prevention.Frontiers in digital health · 2025Review
- Economics and Equity of Large Language Models: Health Care Perspective.Journal of medical Internet research · 2024Article
- Using electronic health records for clinical pharmacology research: Challenges and considerations.Clinical and translational science · 2024Review
- Evaluating MedDRA-to-ICD terminology mappings.BMC medical informatics and decision making · 2024Article
- Automated approach for quality assessment of RDF resources.BMC medical informatics and decision making · 2023Article
- EMR2vec: Bridging the gap between patient data and clinical trial.Computers & industrial engineering · 2021Article
- Using computable knowledge mined from the literature to elucidate confounders for EHR-based pharmacovigilance.Journal of biomedical informatics · 2021Article
- Drugmonizome and Drugmonizome-ML: integration and abstraction of small molecule attributes for drug enrichment analysis and machine learning.Database : the journal of biological databases and curation · 2021Article
- Constructing a knowledge-based heterogeneous information graph for medical health status classification.Health information science and systems · 2020Article
- Development of the Gender, Sex, and Sexual Orientation ontology: Evaluation and workflow.Journal of the American Medical Informatics Association : JAMIA · 2020Article
- AllergyMap: An Open Source Corpus of Allergy Mention Normalizations.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2020Article
- Comparative Analysis and Evaluation of State-of-the-Art Medication Mapping Tools to Transform a Local Medication Terminology to RxNorm.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2020Article
- Enhancing the drug ontology with semantically-rich representations of National Drug Codes and RxNorm unique concept identifiers.BMC bioinformatics · 2019Article
- Comparison of the cohort selection performance of Australian Medicines Terminology to Anatomical Therapeutic Chemical mappings.Journal of the American Medical Informatics Association : JAMIA · 2019Article
- Inferring new relations between medical entities using literature curated term co-occurrences.JAMIA open · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
Abstract
Standardized terminological systems for biomedical information have provided considerable benefits to biomedical applications and research. However, practical use of this information often requires mapping across terminological systems-a complex and time-consuming process. This paper demonstrates the complexity and challenges of mapping across terminological systems in the context of medication information. It provides a review of medication terminological systems and their linkages, then describes a case study in which we mapped proprietary medication codes from an electronic health record to SNOMED CT and the UMLS Metathesaurus. The goal was to create a polyhierarchical classification system for querying an i2b2 clinical data warehouse. We found that three methods were required to accurately map the majority of actively prescribed medications. Only 62.5% of source medication codes could be mapped automatically. The remaining codes were mapped using a combination of semi-automated string comparison with expert selection, and a completely manual approach. Compound drugs were especially difficult to map: only 7.5% could be mapped using the automatic method. General challenges to mapping across terminological systems include (1) the availability of up-to-date information to assess the suitability of a given terminological system for a particular use case, and to assess the quality and completeness of cross-terminology links; (2) the difficulty of correctly using complex, rapidly evolving, modern terminologies; (3) the time and effort required to complete and evaluate the mapping; (4) the need to address differences in granularity between the source and target terminologies; and (5) the need to continuously update the mapping as terminological systems evolve.
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