Evidence map›Paper›PMID 22750525›Full record

ReviewNeurobiology of disease2013

Towards the study of functional brain development in depression: an Interactive Specialization approach.

Michael S Gaffrey, Joan L Luby, Deanna M Barch

Open access · greenAbstract readReview
In one paragraph

Review in Neurobiology of disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Mood Symptom Dimensions and Developmental Differences in Neurocognition in Adolescence.Clinical psychological science : a journal of the Association for Psychological Science · 2023
    Article
  3. Article
  4. Extraction and Fractionation of the SeaweedAdvanced biomedical research · 2022
    Article
  5. Article
  6. Antidepressant-like Effect of a Chalcone Compound, DHIPC and Its Possible Mechanism.Iranian journal of pharmaceutical research : IJPR · 2018
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Disrupted amygdala reactivity in depressed 4- to 6-year-old children.Journal of the American Academy of Child and Adolescent Psychiatry · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Michael S GaffreyDepartment of Psychiatry, Washington University School of Medicine, Saint Louis, MO, USA. gaffreym@wustl.edu
Joan L Luby
Deanna M Barch
Washington University in St. Louis · US

Funding

NEUROIMAGING IN EARLY ONSET DEPRESSION: LONGITUDINAL ASSESSMENT OF BRAIN CHANGESR01MH090786 · NIMH · WASHINGTON UNIVERSITY · PI GILBERT, KIRSTEN, WHALEN, DIANA J · 2010 to 2025
$10.4M
NIMH NIH HHS R01 MH090786
6 · The paper itself

Abstract

Depression is a significant and impairing mood disorder with onset possible as early as age 3 and into adulthood. Given this varying pattern of age of onset, identifying the relationship between brain development and depression across the lifespan has proven elusive. This review identifies some of the factors that may have limited the advancement of our knowledge in this area and discusses how synthesizing established models of depression and normative brain development may help to overcome them. More specifically, it is suggested that current neurobiological models of depression fail to account for the developmental variance associated with early neural network development and the potential influence of experience on this process. The utility of applying an established framework of normative brain development to this topic is described and its potential utility for conceptualizing the influence of depression on brain function across the life span is addressed. Future directions including longitudinal neuroimaging studies of early onset depression and groups at risk for this disorder are proposed.

Indexed as

BrainDepressive DisorderHumansModels, NeurologicalNerve Net

Identifiers

PMID22750525
PMCPMC3480993
OpenAlexW2099976657

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.