ArticleHeart rhythm2012
Intracardiac J-point elevation before the onset of polymorphic ventricular tachycardia and ventricular fibrillation in patients with an implantable cardioverter-defibrillator.
Article in Heart rhythm, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00916435 (Prospective Observational Study of the ICD Intracardiac Electrograms for Prediction of Ventricular Tachyarrhythmias and Congestive Heart Failure), which is not on this map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective Observational Study of the ICD Intracardiac Electrograms for Prediction of Ventricular Tachyarrhythmias and Congestive Heart Failure
Who cites it
8 citing papers in PubMed.
- Dynamic electrocardiogram changes are a novel risk marker for sudden cardiac death.European heart journal · 2024Article
- Fighting against sudden cardiac death: need for a paradigm shift-Adding near-term prevention and pre-emptive action to long-term prevention.European heart journal · 2022Review
- Transverse false tendons in the left ventricular cavity are associated with early repolarization.PloS one · 2015Article
- A novel method to capture the onset of dynamic electrocardiographic ischemic changes and its implications to arrhythmia susceptibility.Journal of the American Heart Association · 2014Article
- Gender modulates the aging effects on different patterns of early repolarization.Heart and vessels · 2014Article
- Construction of intracardiac vectorcardiogram from implantable cardioverter-defibrillator intracardiac electrograms.Journal of electrocardiologyArticle
- Racial differences in sudden cardiac death.Journal of electrocardiologyArticle
- Mechanisms of sudden cardiac death.Indian heart journalReview
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Authors and funding
13 authors.
Funding
Abstract
backgroundThe clinical importance of the J-point elevation on electrocardiogram is controversial.
objectiveTo study intracardiac J-point amplitude before ventricular arrhythmia.
methodsBaseline 12-lead electrocardiogram and far-field right ventricular intracardiac implantable cardioverter-defibrillator electrograms were recorded at rest in 494 patients (mean age 60.4 ± 13.1 years; 360 [72.9%] men) with structural heart disease (278 [56.3%] ischemic cardiomyopathy) who received primary (463 [93.9%] patients) or secondary prevention implantable cardioverter-defibrillator. Ten-second intracardiac far-field electrograms before the onset of arrhythmia were compared with the baseline. The J-point amplitude was measured on the baseline 12-lead surface electrocardiogram and the intracardiac far-field electrogram. The relative J-point amplitude was calculated as the ratio of J-point amplitude to peak-to-peak R-wave.
resultsThe paired t test showed that the relative intracardiac J-point amplitude was significantly higher before polymorphic ventricular tachycardia/ventricular fibrillation (VF) onset (0.28 ± 0.08 vs -0.19 ± 0.39; P = .012) than at baseline. In a mixed-effects logistic regression model, adjusted for multiple episodes per patient, each 10% increase in relative J-point amplitude increased the odds of having ventricular tachycardia/VF by 13% (odds ratio 1.13 [95% confidence interval 1.07-1.19]; P < .0001) and increased the odds of having polymorphic ventricular tachycardia/VF by 27% (odds ratio 1.27 [95% confidence interval 1.11-1.46]; P = .001).
conclusionsThe relative intracardiac J-point amplitude is augmented immediately before the onset of polymorphic ventricular tachycardia/VF in patients with structural heart disease.
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