Evidence map›Paper›PMID 22750084›Full record

ArticleTranslational research : the journal of laboratory and clinical medicine2012

Association of the sirtuin and mitochondrial uncoupling protein genes with carotid intima-media thickness.

David Della-Morte, Chuanhui Dong, Susanne Bartels, Digna Cabral, Susan H Blanton, Ralph L Sacco, Tatjana Rundek

Abstract read
In one paragraph

Article in Translational research : the journal of laboratory and clinical medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. In Search of New Therapeutic Targets in Obesity Treatment: Sirtuins.International journal of molecular sciences · 2016
    Review
  4. Sirtuins and Cancer: Role in the Epithelial-Mesenchymal Transition.Oxidative medicine and cellular longevity · 2016
    Review
  5. Sirtuin/uncoupling protein gene variants and carotid plaque area and morphology.International journal of stroke : official journal of the International Stroke Society · 2015
    Article
  6. Article
  7. Relationship between sirtuin and mitochondrial uncoupling protein genes and carotid artery stiffness.Translational research : the journal of laboratory and clinical medicine · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David Della-MorteDepartment of Neurology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Chuanhui Dong
Susanne Bartels
Digna Cabral
Susan H Blanton
Ralph L Sacco
Tatjana Rundek

Funding

STROKE INCIDENCE AND RISK FACTORS IN A TRI-ETHNIC REGIONR01NS029993 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ELKIND, MITCHELL S, SACCO, RALPH L. · 1993 to 2019
$19.2M
FAMILY STUDY OF STROKE RISK AND CAROTID ATHEROSCLEROSISR01NS040807 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BLANTON, SUSAN HALLORAN, RUNDEK, TATJANA · 2002 to 2022
$12.2M
Stroke Incidence and Risk Factors in a Tri-Ethnic RegionR37NS029993 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ELKIND, MITCHELL S, SACCO, RALPH L. · 2008 to 2014
$12.1M
Genetic Determinants of Subclinical Carotid DiseaseR01NS047655 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI RUNDEK, TATJANA · 2004 to 2008
$1.5M
Genetics Determinants of Extreme Phenotypes of Subclinical AtherosclerosisK24NS062737 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI RUNDEK, TATJANA · 2009 to 2013
$975k
NINDS NIH HHS K24 NS062737NINDS NIH HHS NS062737NINDS NIH HHS R01 NS029993NINDS NIH HHS R01 NS040807NINDS NIH HHS R01 NS047655NINDS NIH HHS R37 NS029993
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Carotid Intima-Media ThicknessAgedCarotid ArteriesCarotid Artery DiseasesFemaleHumansIon ChannelsMaleMitochondrial ProteinsPolymorphism, GeneticSex FactorsSirtuin 3SirtuinsUncoupling Protein 1Uncoupling Protein 2Ion ChannelsMitochondrial ProteinsSIRT3 protein, humanSirtuin 3SirtuinsUncoupling Protein 1Uncoupling Protein 2

Identifiers

PMID22750084
PMCPMC4112455

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.