Evidence map›Paper›PMID 22748656›Full record

ReviewNeurosurgery clinics of North America2012

Nanotechnology applications for glioblastoma.

Edjah K Nduom, Alexandros Bouras, Milota Kaluzova, Costas G Hadjipanayis

Abstract readReview
In one paragraph

Review in Neurosurgery clinics of North America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Precision Oncology: Advances in Drug Delivery and Imaging.Recent advances in drug delivery and formulation · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Edjah K NduomDepartment of Neurosurgery, Emory University School of Medicine, Winship Cancer Institute of Emory University, Atlanta, GA 30322, USA.
Alexandros Bouras
Milota Kaluzova
Costas G Hadjipanayis

Funding

HSV-Mediated Chemoradiosensitivity Human Glioma ModelK08NS053454 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HADJIPANAYIS, CONSTANTINOS GEORGE · 2006 to 2010
$670k
NINDS NIH HHS K08 NS053454NINDS NIH HHS NS053454
6 · The paper itself

Abstract

Glioblastoma remains one of the most difficult cancers to treat and represents the most common primary malignancy of the brain. Although conventional treatments have found modest success in reducing the initial tumor burden, infiltrating cancer cells beyond the main mass are responsible for tumor recurrence and ultimate patient demise. Targeting residual infiltrating cancer cells requires the development of new treatment strategies. The emerging field of cancer nanotechnology holds promise in the use of multifunctional nanoparticles for imaging and targeted therapy of glioblastoma. This article examines the current state of nanotechnology in the treatment of glioblastoma and directions of further study.

Indexed as

BrachytherapyBrain NeoplasmsContrast MediaDrug Delivery SystemsGene Transfer TechniquesGlioblastomaHumansNanoparticlesNanotechnologyPhototherapyContrast Media

Identifiers

PMID22748656
PMCPMC3473084

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.