ArticleGenome biology2012
The role of longitudinal cohort studies in epigenetic epidemiology: challenges and opportunities.
Article in Genome biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A Systematic Review and Meta-Analysis Investigating the Relationship between Exposures to Chemical and Non-Chemical Stressors during Prenatal Development and Childhood Externalizing Behaviors.International journal of environmental research and public health · 2020Pooled it
- The role of oxytocin receptor gene (OXTR) DNA methylation (DNAm) in human social and emotional functioning: a systematic narrative review.BMC psychiatry · 2018Pooled it
- Breastfeeding effects on DNA methylation in the offspring: A systematic literature review.PloS one · 2017Pooled it
- Mode of delivery affected questionnaire response rates in a birth cohort study.Journal of clinical epidemiology · 2017Trial
- ExposoGenomics: integrating genome and exposome as jointly dynamic systems for causal discovery and precision health.Human genomics · 2026Review
- Role of epigenetic markers in cardiovascular disease following hypertensive disorders of pregnancy.Epigenomics · 2025Review
- Environmental Xenobiotics and Epigenetic Modifications: Implications for Human Health and Disease.Journal of xenobiotics · 2025Review
- Human genetics and epigenetics of alcohol use disorder.The Journal of clinical investigation · 2024Review
- A systematic scientometric review of paternal inheritance of acquired metabolic traits.BMC biology · 2023Review
- Using epigenomics to understand cellular responses to environmental influences in diseases.PLoS genetics · 2023Review
- Social Epigenomics: Conceptualizations and Considerations for Oral Health.Journal of dental research · 2022Review
- DNA methylation signatures of adolescent victimization: analysis of a longitudinal monozygotic twin sample.Epigenetics · 2021Article
- Social epigenomics: are we at an impasse?Epigenomics · 2021Review
- Ten Years of EWAS.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
- Clinical epigenomics for cardiovascular disease: Diagnostics and therapies.Journal of molecular and cellular cardiology · 2021Review
- Epigenome-wide change and variation in DNA methylation in childhood: trajectories from birth to late adolescence.Human molecular genetics · 2021Article
- Impact of maternal dietary counseling in the first year of life on DNA methylation in a cohort of children.Genetics and molecular biology · 2021Article
- Intergenerational transmission: Theoretical and methodological issues and an introduction to four Dutch cohorts.Developmental cognitive neuroscience · 2020Review
- The LifeCycle Project-EU Child Cohort Network: a federated analysis infrastructure and harmonized data of more than 250,000 children and parents.European journal of epidemiology · 2020Article
- The National Health and Resilience in Veterans Study: A Narrative Review and Future Directions.Frontiers in psychiatry · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Longitudinal cohort studies are ideal for investigating how epigenetic patterns change over time and relate to changing exposure patterns and the development of disease. We highlight the challenges and opportunities in this approach.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.