Evidence map›Paper›PMID 22746336›Full record

ReviewAnnual review of microbiology2012

RNA interference pathways in fungi: mechanisms and functions.

Shwu-Shin Chang, Zhenyu Zhang, Yi Liu

Abstract readReview
In one paragraph

Review in Annual review of microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed
12.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

128 citing papers in PubMed, 250 citations in OpenAlex.

  1. Review
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  9. Article
  10. Fungal Argonaute proteins act in bidirectional cross-kingdom RNA interference during plant infection.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. The infection of mycovirus down regulatesFrontiers in plant science · 2025
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shwu-Shin ChangDepartment of Physiology, The University of Texas Southwestern Medical Center, Dallas, 75390, USA.
Zhenyu Zhang
Yi Liu
The University of Texas Southwestern Medical Center · US

Funding

Transcriptional and Posttranscriptional Regulation of Neurospora Circadian ClockR01GM068496 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI LIU, YI · 2003 to 2015
$4.5M
MOLECULAR MECHANISMS OF THE NEUROSPORA CIRCADIAN CLOCKR01GM062591 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI LIU, YI · 2001 to 2013
$3.8M
NIGMS NIH HHS R01 GM062591NIGMS NIH HHS R01 GM068496
6 · The paper itself

Abstract

RNA interference (RNAi) is a conserved eukaryotic gene regulatory mechanism that uses small noncoding RNAs to mediate posttranscriptional/transcriptional gene silencing. The fission yeast Schizosaccharomyces pombe and the filamentous fungus Neurospora crassa have served as important model systems for RNAi research. Studies on these two organisms and other fungi have contributed significantly to our understanding of the mechanisms and functions of RNAi in eukaryotes. In addition, surprisingly diverse RNAi-mediated processes and small RNA biogenesis pathways have been discovered in fungi. In this review, we give an overview of different fungal RNAi pathways with a focus on their mechanisms and functions.

Indexed as

Gene Expression Regulation, FungalRNA InterferenceNeurospora crassaRNA, FungalRNA, MessengerSchizosaccharomycesRNA, FungalRNA, Messenger

Identifiers

PMID22746336
PMCPMC4617789
OpenAlexW2170124792

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.