Evidence map›Paper›PMID 22746262›Full record

Trial reportHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2013

Project enhance: a randomized controlled trial of an individualized HIV prevention intervention for HIV-infected men who have sex with men conducted in a primary care setting.

Steven A Safren, Conall M O'Cleirigh, Margie Skeer, Steven A Elsesser, Kenneth H Mayer

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 4 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 4 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
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  20. Online focus groups as an HIV prevention program for gay, bisexual, and queer adolescent males.AIDS education and prevention : official publication of the International Society for AIDS Education · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Steven A SafrenDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. ssafren@partners.org
Conall M O'Cleirigh
Margie Skeer
Steven A Elsesser
Kenneth H Mayer
Fenway Health · USHarvard University · USJohn Brown University · USMassachusetts General Hospital · US

Funding

Enhancing HIV Prevention Among High-Risk HIV+ MenR01MH068746 · NIMH · FENWAY COMMUNITY HEALTH CENTER · PI MAYER, KENNETH H · 2003 to 2007
$2.8M
NIMH NIH HHS 5R01MH068746-05NIMH NIH HHS R01 MH068746
6 · The paper itself

Abstract

objectiveMen who have sex with men (MSM) are the largest group of individuals in the U.S. living with HIV and have the greatest number of new infections. This study was designed to test a brief, culturally relevant prevention intervention for HIV-infected MSM, which could be integrated into HIV care.

methodHIV-infected MSM who received HIV care in a community health center (N = 201), and who reported HIV sexual transmission-risk behavior (TRB) in the prior 6 months, were randomized to receive the intervention or treatment as usual. The intervention, provided by a medical social worker, included proactive case management for psychosocial problems, counseling about living with HIV, and HIV TRB risk reduction. Participants were followed every 3 months for one year.

resultsParticipants, regardless of study condition, reported reductions in HIV TRB, with no significant differential effect by condition in primary intent-to-treat analyses. When examining moderators, the intervention was differentially effective in reducing HIV TRB for those who screened in for baseline depression, but this was not the case for those who did not screen in for depression.

conclusionsThe similar level of reduction in HIV TRB in the intervention and control groups, consistent with other recent secondary prevention interventions, speaks to the need for new, creative designs, or more potent interventions in secondary HIV prevention trials, as the control group seemed to benefit from risk assessment, study contact, and referrals provided by study staff. The differential finding for those with depression may suggest that those without depression could reap benefits from limited interventions, but those with a comorbid psychiatric diagnosis may require additional interventions to modify their sexual risk behaviors.

Indexed as

AdultAgedCounselingDepressionFollow-Up StudiesHIV InfectionsHomosexuality, MaleHumansMaleMiddle AgedPrimary Health CareRisk Reduction BehaviorRisk-TakingSexual BehaviorTreatment Outcome

Identifiers

PMID22746262
PMCPMC3651590
OpenAlexW2113157982

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.