Evidence map›Paper›PMID 22745836›Full record

ReviewPLoS neglected tropical diseases2012

Loop-mediated isothermal amplification technology: towards point of care diagnostics.

Zablon Kithinji Njiru

Registry-linked trialAbstract readReview
In one paragraph

Review in PLoS neglected tropical diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03356665 (Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials), which is not on this map. Cited by 123 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
123citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03356665 nacompletednot on this mapstarted 2017, after this paper: background citation

Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: WP2 Passive Case Detection

TypeinterventionalSponsorInstitut de Recherche pour le DeveloppementRan2017 to 2021Enrolled10,700ConditionsAfrican Trypanosomiases, West African, Trypanosomiasis, Sleeping SicknessArmsRapid diagnostic test (RDT), Serological and molecular tests on DBS
3 · Its place in the literature

Who cites it

123 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Rapid Point-of-Care Detection ofAnimals : an open access journal from MDPI · 2026
    Article
  6. DNA polymerase I: structure, activity, and function in bacterial DNA replication and repair.Critical reviews in biochemistry and molecular biology · 2026
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Development and Validation of the MAST ISOPLEXInternational journal of molecular sciences · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

63 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Zablon Kithinji NjiruThe University of Queensland, The School of Veterinary Sciences, Gatton Campus, Queensland, Australia. z.njiru@uq.edu.au

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Point-of-Care SystemsCommunicable DiseasesHumansMolecular Diagnostic TechniquesNucleic Acid Amplification TechniquesTemperature

Identifiers

PMID22745836
PMCPMC3383729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.