ArticleKorean journal of pediatrics2012
Ambient air pollution and allergic diseases in children.
Article in Korean journal of pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 40 citations in OpenAlex.
- The epigenetic-immune-microbiome axis in early life: reprogramming the origins and endotypes of pediatric asthma.Frontiers in immunology · 2026Review
- Bibliometric analysis of the association between air pollution and allergic rhinitis.Global health action · 2025Article
- Understanding the Link Between Allergy and Neurodevelopmental Disorders: A Current Review of Factors and Mechanisms.Frontiers in neurology · 2020Review
- Associations of gestational and the first year of life exposure to ambient air pollution with childhood eczema in Hubei, China.Environmental science and pollution research international · 2019Article
- Maternal Exposure to Particulate Matter during Pregnancy and Adverse Birth Outcomes in the Republic of Korea.International journal of environmental research and public health · 2019Article
- A Closer Look at the Bivariate Association between Ambient Air Pollution and Allergic Diseases: The Role of Spatial Analysis.International journal of environmental research and public health · 2018Article
- Effects of Environmental Air Pollution on Pulmonary Function Level of Residents in Korean Industrial Complexes.International journal of environmental research and public health · 2018Article
- Exposure to NOClinical epigenetics · 2018Article
- Non-allergic rhinitis in children: Epidemiological aspects, pathological features, diagnostic methodology and clinical management.World journal of methodology · 2016Review
- Role of antioxidants on the clinical outcome of patients with perennial allergic rhinitis.Allergy & rhinology (Providence, R.I.) · 2016Article
- The Cohort for Childhood Origin of Asthma and allergic diseases (COCOA) study: design, rationale and methods.BMC pulmonary medicine · 2014Article
- Allergic diseases: the price of civilisational progress.Postepy dermatologii i alergologii · 2014Review
- Determinants of sensitization to allergen in infants and young children.Korean journal of pediatrics · 2014Review
- The impact of environmental and agricultural pollutants on the prevalence of allergic diseases in people from Qassim, KSA.International journal of health sciences · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence of allergic diseases has increased worldwide, a phenomenon that can be largely attributed to environmental effects. Among environmental factors, air pollution due to traffic is thought to be a major threat to childhood health. Residing near busy roadways is associated with increased asthma hospitalization, decreased lung function, and increased prevalence and severity of wheezing and allergic rhinitis. Recently, prospective cohort studies using more accurate measurements of individual exposure to air pollution have been conducted and have provided definitive evidence of the impact of air pollution on allergic diseases. Particulate matter and ground-level ozone are the most frequent air pollutants that cause harmful effects, and the mechanisms underlying these effects may be related to oxidative stress. The reactive oxidative species produced in response to air pollutants can overwhelm the redox system and damage the cell wall, lipids, proteins, and DNA, leading to airway inflammation and hyper-reactivity. Pollutants may also cause harmful effects via epigenetic mechanisms, which control the expression of genes without changing the DNA sequence itself. These mechanisms are likely to be a target for the prevention of allergies. Further studies are necessary to identify children at risk and understand how these mechanisms regulate gene-environment interactions. This review provides an update of the current understanding on the impact of air pollution on allergic diseases in children and facilitates the integration of issues regarding air pollution and allergies into pediatric practices, with the goal of improving pediatric health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.