ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2012
Visual orientation and directional selectivity through thalamic synchrony.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Machine learning discovers numerous new computational principles supporting elementary motion detection.Nature communications · 2026Article
- Impact of Acute Visual Experience on Development of LGN Receptive Fields in the Ferret.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Thalamic bursting and the role of timing and synchrony in thalamocortical signaling in the awake mouse.Neuron · 2022Article
- Rapid Effects of Vagus Nerve Stimulation on Sensory Processing Through Activation of Neuromodulatory Systems.Frontiers in neuroscience · 2022Review
- Feedforward Thalamocortical Connectivity Preserves Stimulus Timing Information in Sensory Pathways.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Temporal Limits of Visual Motion Processing: Psychophysics and Neurophysiology.Vision (Basel, Switzerland) · 2019Article
- STDP Allows Close-to-Optimal Spatiotemporal Spike Pattern Detection by Single Coincidence Detector Neurons.Neuroscience · 2018Article
- Thalamocortical Circuits and Functional Architecture.Annual review of vision science · 2018Review
- Motion processing picks up speed in the brain.Nature · 2018Article
- Article
- Inhibition in Simple Cell Receptive Fields Is Broad and OFF-Subregion Biased.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Article
- On Synchronizing Coupled Retinogeniculocortical Pathways: A Toy Model.Computational intelligence and neuroscience · 2018Article
- Orientation Tuning of Correlated Activity in the Developing Lateral Geniculate Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Causal evidence for retina-dependent and -independent visual motion computations in mouse cortex.Nature neuroscience · 2017Article
- Mechanisms underlying a thalamocortical transformation during active tactile sensation.PLoS computational biology · 2017Article
- Divisive suppression explains high-precision firing and contrast adaptation in retinal ganglion cells.eLife · 2016Article
- Nonlinear computations shaping temporal processing of precortical vision.Journal of neurophysiology · 2016Article
- Microsaccades enable efficient synchrony-based coding in the retina: a simulation study.Scientific reports · 2016Article
- Electrical and Optical Activation of Mesoscale Neural Circuits with Implications for Coding.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Thalamic neurons respond to visual scenes by generating synchronous spike trains on the timescale of 10-20 ms that are very effective at driving cortical targets. Here we demonstrate that this synchronous activity contains unexpectedly rich information about fundamental properties of visual stimuli. We report that the occurrence of synchronous firing of cat thalamic cells with highly overlapping receptive fields is strongly sensitive to the orientation and the direction of motion of the visual stimulus. We show that this stimulus selectivity is robust, remaining relatively unchanged under different contrasts and temporal frequencies (stimulus velocities). A computational analysis based on an integrate-and-fire model of the direct thalamic input to a layer 4 cortical cell reveals a strong correlation between the degree of thalamic synchrony and the nonlinear relationship between cortical membrane potential and the resultant firing rate. Together, these findings suggest a novel population code in the synchronous firing of neurons in the early visual pathway that could serve as the substrate for establishing cortical representations of the visual scene.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.