Evidence map›Paper›PMID 22745328›Full record

ArticleBMJ (Clinical research ed.)2012

High reprint orders in medical journals and pharmaceutical industry funding: case-control study.

Adam E Handel, Sunil V Patel, Julia Pakpoor, George C Ebers, Ben Goldacre, Sreeram V Ramagopalan

Abstract read
In one paragraph

Article in BMJ (Clinical research ed.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Conflicts of interest in clinical practice: lessons learned from cardiovascular medicine.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Adam E HandelWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Sunil V Patel
Julia Pakpoor
George C Ebers
Ben Goldacre
Sreeram V Ramagopalan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the extent to which funding and study design are associated with high reprint orders.

designCase-control study.

settingTop articles by size of reprint orders in seven journals, 2002-09.

participantsLancet, Lancet Neurology, Lancet Oncology (Lancet Group), BMJ, Gut, Heart, and Journal of Neurology, Neurosurgery & Psychiatry (BMJ Group) matched to contemporaneous articles not in the list of high reprint orders.

main outcome measuresFunding and design of randomised controlled trials or other study designs.

resultsMedian reprint orders for the seven journals ranged from 3000 to 126,350. Papers with high reprint orders were more likely to be funded by the pharmaceutical industry than were control papers (industry funding versus other or none: odds ratio 8.64, 95% confidence interval 5.09 to 14.68, and mixed funding versus other or none: 3.72, 2.43 to 5.70).

conclusionsFunding by the pharmaceutical industry is associated with high numbers of reprint orders.

Indexed as

Research DesignResearch Support as TopicBibliometricsCase-Control StudiesDrug IndustryHumansPeriodicals as Topic

Identifiers

PMID22745328
PMCPMC3386142

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.