Evidence map›Paper›PMID 22745228›Full record

ReviewGenetics2013

Whole-genome regression and prediction methods applied to plant and animal breeding.

Gustavo de Los Campos, John M Hickey, Ricardo Pong-Wong, Hans D Daetwyler, Mario P L Calus

Abstract readReview
In one paragraph

Review in Genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 441 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
441citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

441 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
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  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Harnessing artificial intelligence in plant breeding: innovations in digital phenotyping and breeding methodologies.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Review
  13. Article
  14. Bridging tradition and innovation: a review of computer simulations in plant breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Review
  15. Article
  16. Article
  17. Article
  18. Impact of scale parameter for marker variance prior in some Bayesian whole-genome regression methods.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Article
  19. Article
  20. Article

381 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gustavo de Los CamposDepartment of Biostatistics, School of Public Health, University of Alabama, Birmingham, AL 35294, USA. gcampos@uab.edu
John M Hickey
Ricardo Pong-Wong
Hans D Daetwyler
Mario P L Calus

Funding

Statistical Tools for Whole-Genome Prediction of Complex Traits and DiseasesR01GM101219 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DE LOS CAMPOS, GUSTAVO · 2012 to 2017
$1.6M
Factors Affecting Prediction Accuracy of Complex Human Traits and DiseasesR01GM099992 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DE LOS CAMPOS, GUSTAVO · 2012 to 2015
$1.0M
NIGMS NIH HHS R01 GM099992NIGMS NIH HHS R01 GM101219
6 · The paper itself

Abstract

Genomic-enabled prediction is becoming increasingly important in animal and plant breeding and is also receiving attention in human genetics. Deriving accurate predictions of complex traits requires implementing whole-genome regression (WGR) models where phenotypes are regressed on thousands of markers concurrently. Methods exist that allow implementing these large-p with small-n regressions, and genome-enabled selection (GS) is being implemented in several plant and animal breeding programs. The list of available methods is long, and the relationships between them have not been fully addressed. In this article we provide an overview of available methods for implementing parametric WGR models, discuss selected topics that emerge in applications, and present a general discussion of lessons learned from simulation and empirical data analysis in the last decade.

Indexed as

GenomeAnimalsBayes TheoremBreedingModels, GeneticPhenotypePlantsRegression AnalysisSelection, Genetic

Identifiers

PMID22745228
PMCPMC3567727

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.