Evidence map›Paper›PMID 22744868›Full record

ArticleAngewandte Chemie (International ed. in English)2012

A magnetic Gram stain for bacterial detection.

Ghyslain Budin, Hyun Jung Chung, Hakho Lee, Ralph Weissleder

Open access · greenAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 73 citations in OpenAlex.

  1. Article
  2. Surface fibrils on the particles of nucleocytoviruses: A review.Experimental biology and medicine (Maywood, N.J.) · 2023
    Review
  3. Article
  4. Fc-MBL-modified FeMikrochimica acta · 2022
    Article
  5. Article
  6. Ultra-fast cycling for multiplexed cellular fluorescence imaging.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2020
    Article
  7. Ultra-fast Cycling for Multiplexed Cellular Fluorescence Imaging.Angewandte Chemie (International ed. in English) · 2020
    Article
  8. Article
  9. Article
  10. Article
  11. Rational Design of Materials Interface for Efficient Capture of Circulating Tumor Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2015
    Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. μHall chip for sensitive detection of bacteria.Advanced healthcare materials · 2013
    Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ghyslain BudinCenter for Systems Biology, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA.
Hyun Jung Chung
Hakho Lee
Ralph Weissleder
Center for Systems Biology · USMassachusetts General Hospital · US

Funding

StatisticsP50CA086355 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, MD, PHD, RALPH · 2000 to 2015
$27.8M
Novel Clickdyes for Biomedical SensingR01EB010011 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, MD, PHD, RALPH · 2010 to 2017
$3.1M
NCI NIH HHS 2P50CA086355NCI NIH HHS P50 CA086355NIBIB NIH HHS R01 EB010011
6 · The paper itself

Abstract

Magnetizing: Bacteria are often classified into gram-positive and gram-negative strains by staining with crystal violet (CV). The described bioorthogonal modification of CV with trans-cyclooctene (TCO) can be used to render gram-positive bacteria magnetic with tetrazine-functionalized magnetic nanoparticles (MNP-Tz). This method allows class-specific automated magnetic detection and magnetic separation.

Indexed as

CyclooctanesEscherichia coliGentian VioletMagnetic Resonance SpectroscopyMagnetite NanoparticlesMolecular StructureStaphylococcus aureusStereoisomerismCyclooctanesGentian VioletMagnetite Nanoparticles

Identifiers

PMID22744868
PMCPMC3496380
OpenAlexW2148680889

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.