Evidence map›Paper›PMID 22744722›Full record

ReviewMycopathologia2012

A mucormycosis case in a cirrhotic patient successfully treated with posaconazole and review of published literature.

Shang-Yi Lin, Po-Liang Lu, Kun-Bow Tsai, Chun-Yu Lin, Wei-Ru Lin, Tun-Chieh Chen, Ya-Ting Chang, Chung-Hao Huang, Chi-Yu Chen, Chung-Chih Lai and 1 more

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Mycopathologia, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. A fatal case of disseminated pulmonary and renal mucormycosis caused by Rhizopus microspores.Revista do Instituto de Medicina Tropical de Sao Paulo · 2023
    Article
  3. Article
  4. Pre-Existing Liver Disease and Toxicity of Antifungals.Journal of fungi (Basel, Switzerland) · 2018
    Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Shang-Yi LinDivision of Infectious Diseases, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Po-Liang Lu
Kun-Bow Tsai
Chun-Yu Lin
Wei-Ru Lin
Tun-Chieh Chen
Ya-Ting Chang
Chung-Hao Huang
Chi-Yu Chen
Chung-Chih Lai
Yen-Hsu Chen
Kaohsiung Medical University · TWKaohsiung Medical University Chung-Ho Memorial Hospital · TWKaohsiung Municipal Hsiao-Kang Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucormycosis is an invasive fungal infection associated with a high mortality rate, especially in immunocompromised hosts. Mucormycosis rarely occurs in cirrhotic patients. Here, we report a case of mucormycosis with underlying liver cirrhosis and diabetes mellitus. The patient suffered from maxillary sinusitis and osteomyelitis, and the infection was successfully treated with antifungal agents, surgical debridement, and hyperbaric oxygen therapy. The antifungal treatments used were liposomal amphotericin B, itraconazole, and posaconazole. Although our patient had liver cirrhosis (Child-Pugh classification B), no hepatic decompensation was developed during the treatment course of posaconazole. This is the first report of the safe and effective use of posaconazole for the treatment of mucormycosis in a cirrhotic patient.

Indexed as

AdolescentAdultAgedAntifungal AgentsDiabetes ComplicationsFemaleHumansLiver CirrhosisMaleMiddle AgedMucoralesMucormycosisTriazolesAntifungal AgentsposaconazoleTriazoles

Identifiers

PMID22744722
OpenAlexW2023305410

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.