ReviewMycopathologia2012
Mucor irregularis infection and lethal midline granuloma: a case report and review of published literature.
Review in Mycopathologia, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 31 citations in OpenAlex.
- First report of rhino-orbital mucormycosis caused byCurrent medical mycology · 2022Article
- Laboratory diagnosis of mucormycosis: Present perspective.Journal of family medicine and primary care · 2022Review
- Rhino-Orbital-Cerebral Mycosis and Extranodal Natural Killer or/and T-Cell Lymphoma, Nasal Type.Frontiers in medicine · 2022Article
- Article
- Review
- Case Report:Frontiers in medicine · 2021Article
- Fatal Rhinofacial Mycosis Due toFrontiers in microbiology · 2020Article
- Challenges in the diagnosis and treatment of mucormycosis.Medical mycology · 2018Review
- Successful Treatment by Surgery of a Primary Cutaneous Mucormycosis Caused by Mucor irregularis.Mycopathologia · 2018Article
- The influence of the mating type on virulence of Mucor irregularis.Scientific reports · 2017Article
- Changing Epidemiology of Mucoralean Fungi: Chronic Cutaneous Infection Caused by Mucor irregularis.Mycopathologia · 2015Article
- Mucor irregularis-associated cutaneous mucormycosis: Case report and review.Medical mycology case reports · 2014Article
- Mucor irregularis infection around the inner canthus cured by amphotericin B: a case report and review of published literatures.Mycopathologia · 2014Review
- Drug combinations against Mucor irregularis in vitro.Antimicrobial agents and chemotherapy · 2013Article
- Taxonomy and epidemiology of Mucor irregularis, agent of chronic cutaneous mucormycosis.Persoonia · 2013Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mucor irregularis (Rhizomucor variabilis) infection and lethal midline granuloma (LMG) are characterized by progressive swelling, ulceration, and destruction of the central face that is usually fatal. Pathological features are inflammation, necrosis, and granulation. LMG has been called by various names, and in recent years, it has been known as NK/T cell lymphoma. However, diagnosis still relies on the progressive necrosis course rather than malignancy in histology. The disease has long challenged physicians, particularly when it worsens with radiotherapy or chemotherapy but sometimes achieves total remission without anti-malignancy therapies. We describe a 35-year-old man who had typical clinical-pathological symptoms of LMG, which turned out to be primary M. irregularis infection; that was diagnosed by positive tissue culture and fungal elements in histology. The patient was successfully treated with antifungal therapy (liposomal amphotericin B, total 4,600 mg and amphotericin B total 277 mg, over a duration of 70 days). We hereby review current knowledge about the epidemiology, clinical manifestations, radiographic characteristics, and pathologic features of LMG with those of M. irregularis infection and their associations. We conclude that primary M. irregulars infection can mimic the clinico-pathological symptoms of LMG and the condition responds favorably to aggressive antifungal therapy.
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