ReviewThe Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses2012
The impact of inflammation on cognitive function in older adults: implications for healthcare practice and research.
Review in The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 175 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
175 citing papers in PubMed, 7 syntheses or guidelines pooled it, 303 citations in OpenAlex.
- Beyond the beats: a systematic review of the underlying inflammatory pathways between atrial fibrillation and cognitive decline.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- Chronic obstructive pulmonary disease as a risk factor for cognitive impairment: a systematic review and meta-analysis.BMJ open respiratory research · 2024Pooled it
- Neuropsychological deficits in patients with persistent COVID-19 symptoms: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- COVID-19 associated cognitive impairment: A systematic review.Cortex; a journal devoted to the study of the nervous system and behavior · 2022Pooled it
- Fatigue and cognitive impairment in Post-COVID-19 Syndrome: A systematic review and meta-analysis.Brain, behavior, and immunity · 2022Pooled it
- Association between dietary inflammatory index and cognitive impairment: A meta-analysis.Frontiers in aging neuroscience · 2022Pooled it
- Metabolic syndrome and cognition: A systematic review across cognitive domains and a bibliometric analysis.Frontiers in psychology · 2022Pooled it
- Effects of 12-week exercise on Meteorin-like levels, inflammation, and functional capacity in older adults: Korean national aging project randomized controlled study.European geriatric medicine · 2025Trial
- Trial
- Feasibility and Preliminary Efficacy of American Elderberry Juice for Improving Cognition and Inflammation in Patients with Mild Cognitive Impairment.International journal of molecular sciences · 2024Trial
- Trial
- How Does Dietary Intake Relate to Dispositional Optimism and Health-Related Quality of Life in GermlineNutrients · 2023Trial
- Circulating Mediators of Apoptosis and Inflammation in Aging; Physical Exercise Intervention.International journal of environmental research and public health · 2021Trial
- The enhancing effects of Biobran/MGN-3, an arabinoxylan rice bran, on healthy old adults' health-related quality of life: a randomized, double-blind, placebo-controlled clinical trial.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Trial
- Supplementation with eicosapentaenoic acid and docosahexaenoic acid reduces high levels of circulating proinflammatory cytokines in aging adults: A randomized, controlled study.Prostaglandins, leukotrienes, and essential fatty acids · 2018Trial
- The Inflammatory Potential of the Diet at Midlife Is Associated with Later Healthy Aging in French Adults.The Journal of nutrition · 2018Trial
- Trial
- Article
- Long-term risk of dementia following encephalitis: a large-scale retrospective cohort study of electronic health records.Journal of neurology · 2026Article
- Longitudinal food insecurity patterns and cognitive performance among midlife Latina women: Findings from the CHAMACOS Maternal Cognition Study.Journal of Alzheimer's disease : JAD · 2026Article
115 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Accumulating evidence suggests that levels of inflammation, an immune response, increase with age throughout the body and the brain. The effects of inflammation on the brain, both acute and chronic, have been associated with cognitive decline and risk of dementia in older adults. Factors believed to increase inflammation include certain health-related behaviors, such as smoking, poor diet, and inactivity as well as health conditions like diabetes, hypertension, and chronic obstructive pulmonary disease, most of which require medical intervention and monitoring. As such, nurses and healthcare professionals are likely to encounter patients who are at a high risk for future development of inflammation-related cognitive decline. A review of inflammatory processes and their relation to cognitive function in older adults is provided, along with factors that may increase or reduce inflammation. Implications for practice and research are discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.