ArticleThe European respiratory journal2013
Case-finding options for COPD: results from the Burden of Obstructive Lung Disease study.
Article in The European respiratory journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03355677 (A Clinical Interventional Study Into Airways Disease Case Finding and Complex Case Management), which is not on this map. Cited by 31 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Clinical Interventional Study Into Airways Disease Case Finding and Complex Case Management
Who cites it
31 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Economic evaluations of screening and case-finding for Chronic Obstructive Pulmonary Disease (COPD): a systematic review.NPJ primary care respiratory medicine · 2026Pooled it
- Joint statement for the diagnosis, management, and prevention of chronic obstructive pulmonary disease for Gulf Cooperation Council countries and Middle East-North Africa region, 2017.International journal of chronic obstructive pulmonary disease · 2017Guideline
- Pooled it
- Effectiveness of case finding strategies for COPD in primary care: a systematic review and meta-analysis.NPJ primary care respiratory medicine · 2015Pooled it
- Diagnostic accuracy of a pocket screening spirometer in diagnosing chronic obstructive pulmonary disease in general practice: a cross sectional validation study using tertiary care as a reference.BMC family practice · 2016Trial
- The Use of Lung Cancer Screening to Increase Chronic Obstructive Pulmonary Disease Diagnosis in Veterans Affairs Primary Care.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2025Article
- Effectiveness of adding a peak flow meter for the identification of patients with chronic obstructive pulmonary disease in real-world clinical practice.BMC pulmonary medicine · 2025Article
- The Role of Pulmonary Function Testing in the Diagnosis and Management of COPD.Respiratory care · 2023Review
- Article
- Challenges in the Implementation of Chronic Obstructive Pulmonary Disease Guidelines in Low- and Middle-Income Countries: An Official American Thoracic Society Workshop Report.Annals of the American Thoracic Society · 2021Article
- Vitamin D deficiency is associated with chronic obstructive pulmonary disease and exacerbation of COPD.The clinical respiratory journal · 2021Article
- Cost Effectiveness of Case Detection Strategies for the Early Detection of COPD.Applied health economics and health policy · 2021Article
- Prevalence of different comorbidities in chronic obstructive pulmonary disease among Shahrekord PERSIAN cohort study in southwest Iran.Scientific reports · 2021Article
- Global Initiative for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease. The 2020 GOLD Science Committee Report on COVID-19 and Chronic Obstructive Pulmonary Disease.American journal of respiratory and critical care medicine · 2021Review
- Review
- GPs should not try to detect mild COPD.NPJ primary care respiratory medicine · 2020Article
- A Novel Case-Finding Instrument for Chronic Obstructive Pulmonary Disease in Low- and Middle-Income Country Settings.International journal of chronic obstructive pulmonary disease · 2020Article
- An accurate prediction model to identify undiagnosed at-risk patients with COPD: a cross-sectional case-finding study.NPJ primary care respiratory medicine · 2019Article
- Assessing Airflow Limitation among Smokers in a Primary Care Setting.The Malaysian journal of medical sciences : MJMS · 2018Article
- Observational
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
This study aimed to compare strategies for chronic obstructive pulmonary disease (COPD) case finding using data from the Burden of Obstructive Lung Disease study. Population-based samples of adults aged ≥40 yrs (n = 9,390) from 14 countries completed a questionnaire and spirometry. We compared the screening efficiency of differently staged algorithms that used questionnaire data and/or peak expiratory flow (PEF) data to identify persons at risk for COPD and, hence, needing confirmatory spirometry. Separate algorithms were fitted for moderate/severe COPD and for severe COPD. We estimated the cost of each algorithm in 1,000 people. For moderate/severe COPD, use of questionnaire data alone permitted high sensitivity (97%) but required confirmatory spirometry in 80% of participants. Use of PEF necessitated confirmatory spirometry in only 19-22% of subjects, with 83-84% sensitivity. For severe COPD, use of PEF achieved 91-93% sensitivity, requiring confirmatory spirometry in <9% of participants. Cost analysis suggested that a staged screening algorithm using only PEF initially, followed by confirmatory spirometry as needed, was the most cost-effective case-finding strategy. Our results support the use of PEF as a simple, cost-effective initial screening tool for conducting COPD case-finding in adults aged ≥40 yrs. These findings should be validated in real-world settings such as the primary care environment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.