Evidence map›Paper›PMID 22743313›Full record

Trial reportThe American journal of clinical nutrition2012

A randomized trial of the effects of an almond-enriched, hypocaloric diet in the treatment of obesity.

Gary D Foster, Kerri Leh Shantz, Stephanie S Vander Veur, Tracy L Oliver, Michelle R Lent, Amy Virus, Philippe O Szapary, Daniel J Rader, Babette S Zemel, Adam Gilden-Tsai

2 registry-linked trialsOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The American journal of clinical nutrition, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 43 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 11 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00194428 phase1 / phase2completednot on this map

Weight and Metabolic Effects of an Almond Enriched Hypocaloric, Low Fat Diet on Overweight and Obese Persons

TypeinterventionalSponsorTemple UniversityRan2005 to 2009Enrolled123ConditionsObesity, Metabolic Syndrome X, Hyperlipidemia, HypertensionArmsAlmond enriched diet, Low fat caloric diet
NCT02501889 nacompletednot on this mapstarted 2015, after this paper: background citation

Walnut Consumption in a Weight Loss Intervention: Effects on Weight Change, Satiety and Potential Mediating Factors

TypeinterventionalSponsorUniversity of California, San DiegoRan2015 to 2017Enrolled100ConditionsOverweight and ObesityArmsWalnut-rich weight loss diet, Standard weight loss diet
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 11 syntheses or guidelines pooled it, 98 citations in OpenAlex.

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  10. Nut consumption for the primary prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Gary D FosterTemple University, Center for Obesity Research and Education, Philadelphia, PA 19140, USA. gfoster@temple.edu
Kerri Leh Shantz
Stephanie S Vander Veur
Tracy L Oliver
Michelle R Lent
Amy Virus
Philippe O Szapary
Daniel J Rader
Babette S Zemel
Adam Gilden-Tsai
Temple University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncreased consumption of nuts has been advocated because of their health benefits, but the role of nuts in the treatment of obesity is unclear given their high energy density.

objectiveThis study was designed to evaluate the effects of a hypocaloric, almond-enriched diet (AED) compared with a hypocaloric nut-free diet (NFD) on body weight and cardiovascular disease risk factors in the context of an 18-mo behavioral weight-management program.

designOverweight and obese individuals [n = 123; age = 46.8 y, BMI (in kg/m(2)) = 34.0] were randomly assigned to consume an AED or NFD and instructed in traditional behavioral methods of weight control. Anthropometric and metabolic measurements were made at baseline, 6 mo, and 18 mo.

resultsThose in the AED group lost slightly but significantly less weight than did those in the NFD group at 6 mo (-5.5 compared with -7.4 kg; P = 0.04), but there were no differences at 18 mo. No significant differences in body composition were found between the groups at 6 or 18 mo. The AED, compared with the NFD, was associated with greater reductions in total cholesterol (P = 0.03), total:HDL cholesterol (P = 0.02), and triglycerides (P = 0.048) at 6 mo, and no differences were observed between the groups at 18 mo.

conclusionsThe AED and NFD groups experienced clinically significant and comparable weight loss at 18 mo. Despite smaller weight loss in the AED group at 6 mo, the AED group experienced greater improvements in lipid profiles. This trial was registered at clinicaltrials.gov as NCT00194428.

Indexed as

Caloric RestrictionDietNutsAdultBody CompositionBody Mass IndexBody WeightCardiovascular DiseasesCholesterol, HDLCholesterol, LDLEnergy IntakeFemaleHumansMaleMiddle AgedObesityCholesterol, HDLCholesterol, LDLTriglycerides

Identifiers

PMID22743313
PMCPMC3396441
OpenAlexW2115132399

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.