Evidence map›Paper›PMID 22743224›Full record

ArticleBioinformatics (Oxford, England)2012

GO-Elite: a flexible solution for pathway and ontology over-representation.

Alexander C Zambon, Stan Gaj, Isaac Ho, Kristina Hanspers, Karen Vranizan, Chris T Evelo, Bruce R Conklin, Alexander R Pico, Nathan Salomonis

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 163 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
163citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

163 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. ENOX2 NADH Oxidase: A BCR-ABL1-Dependent Cell Surface and Secreted Redox Protein in Chronic Myeloid LeukemiaTurkish journal of haematology : official journal of Turkish Society of Haematology · 2023
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103 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexander C ZambonDepartments of Pharmacology and Medicine, University of California at San Diego, La Jolla, CA 92093, USA.
Stan Gaj
Isaac Ho
Kristina Hanspers
Karen Vranizan
Chris T Evelo
Bruce R Conklin
Alexander R Pico
Nathan Salomonis

Funding

GenMAPP-CS, a dynamic resource pathway analysisR01GM080223 · NIGMS · J. DAVID GLADSTONE INSTITUTES · PI CONKLIN, BRUCE R · 2007 to 2010
$2.0M
GenMAPP: A tool for pathway analysis of genomic dataR01HG003053 · NHGRI · J. DAVID GLADSTONE INSTITUTES · PI CONKLIN, BRUCE R · 2004 to 2006
$1.3M
NHGRI NIH HHS HG003053NHGRI NIH HHS R01 HG003053NIGMS NIH HHS GM080223NIGMS NIH HHS GM080223-06S1NIGMS NIH HHS R01 GM080223
6 · The paper itself

Abstract

unlabelledWe introduce GO-Elite, a flexible and powerful pathway analysis tool for a wide array of species, identifiers (IDs), pathways, ontologies and gene sets. In addition to the Gene Ontology (GO), GO-Elite allows the user to perform over-representation analysis on any structured ontology annotations, pathway database or biological IDs (e.g. gene, protein or metabolite). GO-Elite exploits the structured nature of biological ontologies to report a minimal set of non-overlapping terms. The results can be visualized on WikiPathways or as networks. Built-in support is provided for over 60 species and 50 ID systems, covering gene, disease and phenotype ontologies, multiple pathway databases, biomarkers, and transcription factor and microRNA targets. GO-Elite is available as a web interface, GenMAPP-CS plugin and as a cross-platform application. AVAILABILITY: http://www.genmapp.org/go_elite

Indexed as

Databases, GeneticSoftwareComputational BiologyInformation Storage and RetrievalInternetUser-Computer InterfaceVocabulary, Controlled

Identifiers

PMID22743224
PMCPMC3413395

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.