Evidence map›Paper›PMID 22743067›Full record

ReviewTrends in plant science2012

Alternative splicing in plants--coming of age.

Naeem H Syed, Maria Kalyna, Yamile Marquez, Andrea Barta, John W S Brown

Open access · hybridAbstract readReview
In one paragraph

Review in Trends in plant science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 258 papers.

0numbers the graph read from it
0cells of the map it votes in
258citing papers in PubMed
13.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

258 citing papers in PubMed, 516 citations in OpenAlex.

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  10. Review
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  13. Alternative splicing-mediated regulation of a novel allele of Badh2 drives moderate accumulation of 2-AP in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
  14. Article
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  17. Comprehensive analysis of alternative splicing inFrontiers in plant science · 2025
    Article
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  20. Article

198 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Naeem H SyedDivision of Plant Sciences, University of Dundee at the James Hutton Institute, Invergowrie, Dundee DD2 5DA, Scotland, UK.
Maria Kalyna
Yamile Marquez
Andrea Barta
John W S Brown
Medical University of Vienna · ATJames Hutton Institute · GB

Funding

Austrian Science Fund FWF I 254Biotechnology and Biological Sciences Research Council BB/G024979/1
6 · The paper itself

Abstract

More than 60% of intron-containing genes undergo alternative splicing (AS) in plants. This number will increase when AS in different tissues, developmental stages, and environmental conditions are explored. Although the functional impact of AS on protein complexity is still understudied in plants, recent examples demonstrate its importance in regulating plant processes. AS also regulates transcript levels and the link with nonsense-mediated decay and generation of unproductive mRNAs illustrate the need for both transcriptional and AS data in gene expression analyses. AS has influenced the evolution of the complex networks of regulation of gene expression and variation in AS contributed to adaptation of plants to their environment and therefore will impact strategies for improving plant and crop phenotypes.

Indexed as

Alternative SplicingGene Expression Regulation, PlantCircadian ClocksEpigenesis, GeneticEvolution, MolecularGenes, PlantNonsense Mediated mRNA DecayPlant ProteinsPlantsPolyploidyProtein StabilityRNA, MessengerRNA, PlantTranscription, GeneticPlant ProteinsRNA, MessengerRNA, Plant

Identifiers

PMID22743067
PMCPMC3466422
OpenAlexW2100137396

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.