Evidence map›Paper›PMID 22742942›Full record

ArticleTransactions of the Royal Society of Tropical Medicine and Hygiene2012

Histoplasmosis among hospitalized febrile patients in northern Tanzania.

Sarah M Lofgren, Emily J Kirsch, Venance P Maro, Anne B Morrissey, Levina J Msuya, Grace D Kinabo, Wilbrod Saganda, Helmut C Diefenthal, Habib O Ramadhani, L Joseph Wheat and 1 more

Open access · greenAbstract read
In one paragraph

Article in Transactions of the Royal Society of Tropical Medicine and Hygiene, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Prevalence ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Invasive Fungal Diseases in Africa: A Critical Literature Review.Journal of fungi (Basel, Switzerland) · 2022
    Article
  12. Hepatic Histoplasmosis: An Update.Journal of clinical and translational hepatology · 2022
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Estimated Burden of Serious Fungal Infections in Ghana.Journal of fungi (Basel, Switzerland) · 2019
    Article
  20. The epidemiology of febrile illness in sub-Saharan Africa: implications for diagnosis and management.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Sarah M LofgrenDivision of Infectious Diseases and International Health, Department of Medicine, Box 102359, Duke University Medical Center, Durham, NC 27710, USA.
Emily J Kirsch
Venance P Maro
Anne B Morrissey
Levina J Msuya
Grace D Kinabo
Wilbrod Saganda
Helmut C Diefenthal
Habib O Ramadhani
L Joseph Wheat
John A Crump
Kilimanjaro Christian Medical Centre · TZDuke Medical Center · USChristian Medical College & Hospital · IN

Funding

Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI Susanna Naggie, GEORGIA Doris TOMARAS · 2005 to 2026
$50.5M
Viral and Host Determinants of HIV-1 TransmissionU01AI067854 · NIAID · DUKE UNIVERSITY · PI HARRISON, STEPHEN COPLAN · 2005 to 2005
$14.9M
HIV/AIDS Clinical Trials UnitU01AI069484 · NIAID · DUKE UNIVERSITY · PI BARTLETT, JOHN A · 2007 to 2011
$14.6M
International Clinical Trials UnitU01AI062563 · NIAID · DUKE UNIVERSITY · PI BARTLETT, JOHN A · 2004 to 2007
$4.0M
AIDS International Training and Research ProgramD43TW006732 · FIC · DUKE UNIVERSITY · PI BARTLETT, JOHN A · 2004 to 2012
$2.7M
The Impact and Society Ecology of Bacterial Zoonoses in Northern Tanzania: UnderR01TW009237 · FIC · DUKE UNIVERSITY · PI CRUMP, JOHN ANDREW · 2011 to 2014
$1.7M
FIC NIH HHS D43 TW006732FIC NIH HHS R01 TW009237NIAID NIH HHS P30 AI064518NIAID NIH HHS P30 AI 64518NIAID NIH HHS U01 AI062563NIAID NIH HHS U01 AI067854NIAID NIH HHS U01 AI069484PHS HHS D43 PA-03-018
6 · The paper itself

Abstract

Histoplasmosis may be common in East Africa but the diagnosis is rarely confirmed. We report 9 (0.9%) cases of probable histoplasmosis retrospectively identified among 970 febrile inpatients studied in northern Tanzania. Median (range) age was 31 (6, 44) years, 6 (67%) were female, 6 (67%) HIV-infected; 7 (78%) were clinically diagnosed with tuberculosis or bacterial pneumonia. Histoplasmosis is an important cause of febrile illness in Tanzania but is rarely considered in the differential diagnosis. Increased clinician awareness and availability of reliable diagnostic tests may improve patient outcomes.

Indexed as

AdolescentAdultChildDiagnosis, DifferentialFemaleFeverHistoplasmaHistoplasmosisHIV SeropositivityHospitalizationHumansMaleRetrospective StudiesTanzaniaTuberculosisYoung Adult

Identifiers

PMID22742942
PMCPMC3392419
OpenAlexW1977947115

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.