Evidence map›Paper›PMID 22742621›Full record

ArticleHealth services research2013

Case definitions for acute myocardial infarction in administrative databases and their impact on in-hospital mortality rates.

Amy Metcalfe, Annabelle Neudam, Samantha Forde, Mingfu Liu, Saskia Drosler, Hude Quan, Nathalie Jetté

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Article in Health services research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

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50citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Article
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  7. Cardiovascular Outcomes Associated with Cholinesterase Inhibitor Use in Individuals at High Cardiovascular Risk.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2025
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Amy MetcalfeDepartments of Community Health Sciences and Clinical Neurosciences, University of Calgary, TRW Building 3rd Floor, 3280 Hospital Drive NW, Calgary, AB, Canada, T2N 4Z6. amy.metcalfe@albertahealthservices.ca
Annabelle Neudam
Samantha Forde
Mingfu Liu
Saskia Drosler
Hude Quan
Nathalie Jetté

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

objectiveTo identify validated ICD-9-CM/ICD-10 coded case definitions for acute myocardial infarction (AMI). DATA SOURCES: Ovid Medline (1950-2010) was searched to identify studies that validated acute myocardial infarction (AMI) case definitions. Hospital discharge abstract data and chart data were linked to validate identified AMI definitions. STUDY

designSystematic literature review, chart review, and administrative data analysis. DATA COLLECTION/EXTRACTION

methodsData on sensitivity/specificity/positive and negative predictive values (PPV and NPV) were extracted from previous studies to identify validated case definitions for AMI. These case definitions were validated in administrative data through chart review and applied to hospital discharge data to assess in-hospital mortality. PRINCIPAL

findingsOf the eight ICD-9-CM definitions validated in the literature, use of ICD-9-CM code 410 to define AMI had the highest sensitivity (94 percent) and specificity (99 percent). In our data, ICD-9-CM/ICD-10 codes 410/I21-I22 in all available coding fields had high sensitivity (83.3 percent/82.8 percent) and PPV (82.8 percent/82.2 percent). The in-hospital mortality among AMI patients identified using this case definition was 7.6 percent in ICD-9-CM data and 6.6 percent in ICD-10 data.

conclusionsWe recommend that ICD-9-CM 410 or ICD-10 I21-I22 in the primary diagnosis coding field should be used to define AMI. The use of a consistent validated case definition would improve comparability across studies.

Indexed as

Acute DiseaseDatabases, FactualHospital MortalityHumansInternational Classification of DiseasesMyocardial InfarctionPatient DischargeReproducibility of Results

Identifiers

PMID22742621
PMCPMC3589967

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.