Evidence map›Paper›PMID 22742536›Full record

SynthesisSystematic reviews2012

Mental health outcomes in HIV and childhood maltreatment: a systematic review.

Georgina Spies, Tracie O Afifi, Sarah L Archibald, Christine Fennema-Notestine, Jitender Sareen, Soraya Seedat

Abstract readSystematic Review
In one paragraph

Synthesis in Systematic reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Mediating roles of social support in lives of men who have sex with men living with HIV.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Article
  6. Article
  7. Adverse childhood experiences, mental illness, HIV and offending among female inmates in Durban, South Africa.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2024
    Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Effects of Early-Life Adversities on Neuropsychiatric and Executive Functions in HIV-Positive Adults.Journal of the International Neuropsychological Society : JINS · 2023
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Effects of trauma, economic hardship, and stress on neurocognition and everyday function in HIV.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Georgina SpiesSouth African Research Chairs Initiative (SARChI), PTSD program, Francie van Zijl Drive, Department of Psychiatry, University of Stellenbosch, Cape Town, 7505, South Africa.
Tracie O Afifi
Sarah L Archibald
Christine Fennema-Notestine
Jitender Sareen
Soraya Seedat

Funding

STRUCTURAL NEUROIMAGING COREP30MH062512 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DAVID J MOORE · 2001 to 2026
$50.4M
NIMH NIH HHS P30-MH62512
6 · The paper itself

Abstract

backgroundHigh rates of childhood maltreatment have been documented in HIV-positive men and women. In addition, mental disorders are highly prevalent in both HIV-infected individuals and victims of childhood maltreatment. However, there is a paucity of research investigating the mental health outcomes associated with childhood maltreatment in the context of HIV infection. The present systematic review assessed mental health outcomes in HIV-positive individuals who were victims of childhood maltreatment.

methodsA systematic search of all retrospective, prospective, or clinical trial studies assessing mental health outcomes associated with HIV and childhood maltreatment. The following online databases were searched on 25-31 August 2010: PubMed, Social Science Citation Index, and the Cochrane Library (the Cochrane Central Register of Controlled Trials and the Cochrane Developmental, Psychosocial and Learning Problems, HIV/AIDS, and Depression, Anxiety and Neurosis registers).

resultsWe identified 34 studies suitable for inclusion. A total of 14,935 participants were included in these studies. A variety of mixed mental health outcomes were reported. The most commonly reported psychiatric disorders among HIV-positive individuals with a history of childhood maltreatment included: substance abuse, major depressive disorder, and posttraumatic stress disorder. An association between childhood maltreatment and poor adherence to antiretroviral regimens was also reported in some studies.

conclusionA broad range of adult psychopathology has been reported in studies of HIV-infected individuals with a history of childhood maltreatment. However, a direct causal link cannot be well established. Longer term assessment will better delineate the nature, severity, and temporal relationship of childhood maltreatment to mental health outcomes.

Indexed as

AdultAdult Survivors of Child AbuseFemaleHIV InfectionsHumansMaleMental DisordersPrevalence

Identifiers

PMID22742536
PMCPMC3441909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.