ArticleMolecular microbiology2012
A complex LuxR-LuxI type quorum sensing network in a roseobacterial marine sponge symbiont activates flagellar motility and inhibits biofilm formation.
Article in Molecular microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 43 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
43 citing papers in PubMed, 79 citations in OpenAlex.
- Article
- CerM and Its Antagonist CerN Are New Components of the Quorum Sensing System in Cereibacter sphaeroides, Signaling to the CckA/ChpT/CtrA System.MicrobiologyOpen · 2024Article
- Insights into Adaptive Mechanisms of Extreme Acidophiles Based on Quorum Sensing/Quenching-Related Proteins.mSystems · 2022Article
- Marine Sponges in a Snowstorm - Extreme Sensitivity of a Sponge Holobiont to Marine Oil Snow and Chemically Dispersed Oil Pollution.Frontiers in microbiology · 2022Article
- Impact of Quorum Sensing and Tropodithietic Acid Production on the Exometabolome ofFrontiers in microbiology · 2022Article
- Quorum sensing regulates 'swim-or-stick' lifestyle in the phycosphere.Environmental microbiology · 2020Article
- An improved and highly selective fluorescence assay for measuring phosphatidylserine decarboxylase activity.The Journal of biological chemistry · 2020Article
- Metagenomic Insights Into the Microbial Assemblage Capable of Quorum Sensing and Quorum Quenching in Particulate Organic Matter in the Yellow Sea.Frontiers in microbiology · 2020Article
- Co-dependent and Interdigitated: Dual Quorum Sensing Systems Regulate Conjugative Transfer of the Ti Plasmid and the At Megaplasmid inFrontiers in microbiology · 2020Article
- Cultivation of Sponge-Associated Bacteria fromMarine drugs · 2019Article
- Disruption of N-acyl-homoserine lactone-specific signalling and virulence in clinical pathogens by marine sponge bacteria.Microbial biotechnology · 2019Article
- Genomic blueprints of sponge-prokaryote symbiosis are shared by low abundant and cultivatable Alphaproteobacteria.Scientific reports · 2019Article
- Potential role of host-derived quorum quenching in modulating bacterial colonization in the moon jellyfish Aurelia aurita.Scientific reports · 2019Article
- Quorum Sensing Signaling Alters Virulence Potential and Population Dynamics in Complex Microbiome-Host Interactomes.Frontiers in microbiology · 2019Article
- Increased biofilm formation due to high-temperature adaptation in marine Roseobacter.Nature microbiology · 2018Article
- Review
- Quorum Sensing System ofFrontiers in microbiology · 2018Article
- Comparative Genomics Highlights Symbiotic Capacities and High Metabolic Flexibility of the Marine Genus Pseudovibrio.Genome biology and evolution · 2018Article
- Global occurrence and heterogeneity of the Roseobacter-clade species Ruegeria mobilis.The ISME journal · 2017Article
- Large Diversity and Original Structures of Acyl-Homoserine Lactones in Strain MOLA 401, a MarineFrontiers in microbiology · 2017Article
Corrections and comments
- Erratum issuedChoi, Ohkee [corrected to Choi, Okhee]; Wysoczinski, Christina L [corrected to Wysoczynski, Christina L]
Authors and funding
14 authors at 6 institutions in 2 countries.
Funding
Abstract
Bacteria isolated from marine sponges, including the Silicibacter-Ruegeria (SR) subgroup of the Roseobacter clade, produce N-acylhomoserine lactone (AHL) quorum sensing signal molecules. This study is the first detailed analysis of AHL quorum sensing in sponge-associated bacteria, specifically Ruegeria sp. KLH11, from the sponge Mycale laxissima. Two pairs of luxR and luxI homologues and one solo luxI homologue were identified and designated ssaRI, ssbRI and sscI (sponge-associated symbiont locus A, B and C, luxR or luxI homologue). SsaI produced predominantly long-chain 3-oxo-AHLs and both SsbI and SscI specified 3-OH-AHLs. Addition of exogenous AHLs to KLH11 increased the expression of ssaI but not ssaR, ssbI or ssbR, and genetic analyses revealed a complex interconnected arrangement between SsaRI and SsbRI systems. Interestingly, flagellar motility was abolished in the ssaI and ssaR mutants, with the flagellar biosynthesis genes under strict SsaRI control, and active motility only at high culture density. Conversely, ssaI and ssaR mutants formed more robust biofilms than wild-type KLH11. AHLs and the ssaI transcript were detected in M. laxissima extracts, suggesting that AHL signalling contributes to the decision between motility and sessility and that it may also facilitate acclimation to different environments that include the sponge host.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.