ArticleBiomedical optics express2012
Noninvasive imaging of flowing blood cells using label-free spectrally encoded flow cytometry.
Article in Biomedical optics express, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 59 citations in OpenAlex.
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- Measuring the red blood cell shape in capillary flow using spectrally encoded flow cytometry.Biomedical optics express · 2022Article
- Boundary-Preserved Deep Denoising of Stochastic Resonance Enhanced Multiphoton Images.IEEE journal of translational engineering in health and medicine · 2022Article
- Prospects for Fluorescence MolecularFrontiers in photonics · 2022Article
- Scattering oblique plane microscopy forBiomedical optics express · 2021Article
- Automated White Blood Cell Counting in Nailfold Capillary Using Deep Learning Segmentation and Video Stabilization.Sensors (Basel, Switzerland) · 2020Article
- Imaging human blood cells in vivo with oblique back-illumination capillaroscopy.Biomedical optics express · 2020Article
- Prospects for the Use of Upconverting Nanoparticles as a Contrast Agent for Enumeration of Circulating Cells in vivo.International journal of nanomedicine · 2020Article
- High-throughput label-free flow cytometry based on matched-filter compressive imaging.Biomedical optics express · 2018Article
- Non-invasive detection of severe neutropenia in chemotherapy patients by optical imaging of nailfold microcirculation.Scientific reports · 2018Article
- Fluorescence detection, enumeration and characterization of single circulating cells in vivo: technology, applications and future prospects.Physics in medicine and biology · 2017Article
- In vivo noninvasive microscopy of human leucocytes.Scientific reports · 2017Article
- Classification of biological micro-objects using optical coherence tomography: in silico study.Biomedical optics express · 2017Article
- Measuring sickle cell morphology during blood flow.Biomedical optics express · 2017Article
- Simultaneous two-color stimulated Raman scattering microscopy by adding a fiber amplifier to a 2 ps OPO-based SRS microscope.Optics letters · 2017Article
- Imaging Cytometry of Human Leukocytes with Third Harmonic Generation Microscopy.Scientific reports · 2016Article
- Article
- Velocity measurements in whole blood using acoustic resolution photoacoustic Doppler.Biomedical optics express · 2016Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Optical microscopy of blood cells in vivo provides a unique opportunity for clinicians and researchers to visualize the morphology and dynamics of circulating cells, but is usually limited by the imaging speed and by the need for exogenous labeling of the cells. Here we present a label-free approach for in vivo flow cytometry of blood using a compact imaging probe that could be adapted for bedside real-time imaging of patients in clinical settings, and demonstrate subcellular resolution imaging of red and white blood cells flowing in the oral mucosa of a human volunteer. By analyzing the large data sets obtained by the system, valuable blood parameters could be extracted and used for direct, reliable assessment of patient physiology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.