ArticleOncology letters2012
Gene expression profiling of cancer stem cells in the Du145 prostate cancer cell line.
Article in Oncology letters, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Isolation, cultivation and identification of human lung adenocarcinoma stem cells.Oncology letters · 2015Article
- Enrichment of prostate cancer stem cells from primary prostate cancer cultures of biopsy samples.International journal of clinical and experimental pathology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cancer stem cells (CSCs) that exhibit tumor-initiating properties have been identified in primary prostate cancer and prostate cancer cell lines. CSCs are the root of tumor metastasis and recurrence even in the cases where they constitute a minority of the tumor mass. In this study, putative CSCs were isolated from the Du145 cell line and an Affymetrix microarray was used to investigate their gene expression profile. The results were validated by real-time polymerase chain reaction (PCR). The results of the microarray indicated that 138 genes were upregulated and 93 genes were downregulated in the CSCs. Certain genes that may be significant in the regulation of CSCs from the Du145 cell line were identified. These results may aid the studying of the mechanisms through which CSCs acquire their distinctive properties.
Identifiers
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Registered trials
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