ArticleThe Journal of infectious diseases2012
Reemergence and decline of dengue virus serotype 3 in Puerto Rico.
Article in The Journal of infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Dengue in Latin America: Systematic Review of Molecular Epidemiological Trends.PLoS neglected tropical diseases · 2017Pooled it
- Article
- Dengue Outbreak Caused by Multiple Virus Serotypes and Lineages, Colombia, 2023-2024.Emerging infectious diseases · 2024Article
- 2023-24 dengue outbreak in Valle del Cauca, Colombia caused by multiple virus serotypes and lineages.medRxiv : the preprint server for health sciences · 2024Article
- Travel surveillance uncovers dengue virus dynamics and introductions in the Caribbean.Nature communications · 2024Article
- Travel surveillance uncovers dengue virus dynamics and introductions in the Caribbean.medRxiv : the preprint server for health sciences · 2023Article
- Differential heterologous neutralisation profile against strains within DENV-3 genotype II.Epidemiology and infection · 2021Article
- Genetic Variation in the Domain II, 3' Untranslated Region of Human and Mosquito Derived Dengue Virus Strains in Sri Lanka.Viruses · 2021Article
- Genomic Epidemiology as a Public Health Tool to Combat Mosquito-Borne Virus Outbreaks.The Journal of infectious diseases · 2020Review
- Spatio-temporal distribution analysis of circulating genotypes of dengue virus type 1 in western and southern states of India by a one-step real-time RT-PCR assay.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2019Article
- Development of a Standardized Sanger-Based Method for Partial Sequencing and Genotyping of Dengue Viruses.Journal of clinical microbiology · 2019Article
- Article
- Autochthonous spread of DENV-3 genotype III in Malaysia mitigated by pre-existing homotypic and heterotypic immunity.Epidemiology and infection · 2018Article
- Emergence of the Asian lineage dengue virus type 3 genotype III in Malaysia.BMC evolutionary biology · 2018Article
- Evolutionary history and spatio-temporal dynamics of dengue virus serotypes in an endemic region of Colombia.PloS one · 2018Article
- Dengue virus genomic variation associated with mosquito adaptation defines the pattern of viral non-coding RNAs and fitness in human cells.PLoS pathogens · 2017Article
- Epidemiological Characteristics of Dengue Disease in Latin America and in the Caribbean: A Systematic Review of the Literature.Journal of tropical medicine · 2017Review
- Insights into the molecular evolution of Dengue virus type 4 in Puerto Rico over two decades of emergence.Virus research · 2016Article
- DGV: Dengue Genographic Viewer.Frontiers in microbiology · 2016Article
- Sequential episodes of dengue--Puerto Rico, 2005-2010.The American journal of tropical medicine and hygiene · 2014Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundThe dengue virus serotype 3 (DENV-3) Indian subcontinent strain emerged in Puerto Rico in 1998 after a 21-year absence. The rapid expansion of DENV-3 on the island correlated with the withdrawal of the other serotypes for 7 years. The DENV-3 prevalence declined in 2008 and remains undetected.
methodsWe sequenced complete genomes of 92 DENV-3 clinical isolates to characterize the molecular evolution and phylogeography throughout 10 years of continued sampling (1998–2007).
resultsWe documented 8 distinct lineages that emerged simultaneously and evolved independently. Two of the 8 lineages were highly associated with transient introductions of foreign viruses, and 2 of the 3 endemic lineages covered the entire study period. We found evidence of temporal-geographical clustering only within the 3 endemic lineages. The phylogeography analysis combined with serotype-specific incidence data showed that transmission of a DENV serotype in a given location and time is usually correlated with the absence of the other serotype.
conclusionsOur study shows the cotransmission of DENV-3 lineages through a complex dissemination pattern dissimilar to the evolutionary dynamics of the other serotypes in the island. High virus genetic diversity and a large naive population were underlying factors in the expansion and collapse of DENV-3 in Puerto Rico.
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