ArticleThe Journal of biological chemistry2012
Calcium-induced mechanical change in the neck domain alters the activity of plant myosin XI.
Article in The Journal of biological chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Local anesthetic lidocaine decelerates cytoplasmic streaming inPlant signaling & behavior · 2026Article
- The calmodulin-like proteins, CML13 and CML14 function as myosin light chains for the class XI myosins in Arabidopsis.Plant & cell physiology · 2026Article
- Article
- Exploring the Role of the Plant Actin Cytoskeleton: From Signaling to Cellular Functions.International journal of molecular sciences · 2023Review
- Encoding, transmission, decoding, and specificity of calcium signals in plants.Journal of experimental botany · 2022Review
- Let's shape again: the concerted molecular action that builds the pollen tube.Plant reproduction · 2022Review
- RNAi-Mediated Knockdown of Calreticulin3a Impairs Pollen Tube Growth inInternational journal of molecular sciences · 2022Article
- Review
- Structural Aspects and Prediction of Calmodulin-Binding Proteins.International journal of molecular sciences · 2020Review
- Heterologous transformation ofPlant biotechnology (Tokyo, Japan) · 2020Article
- A calcium-mediated actin redistribution at egg activation in Drosophila.Molecular reproduction and development · 2020Article
- Three CNGC Family Members, CNGC5, CNGC6, and CNGC9, Are Required for Constitutive Growth ofPlant communications · 2020Article
- Functional Diversity of Class XI Myosins in Arabidopsis thaliana.Plant & cell physiology · 2018Article
- Kinesins and Myosins: Molecular Motors that Coordinate Cellular Functions in Plants.Annual review of plant biology · 2018Review
- Egg activation-triggered shape change in the Dictyota dichotoma (Phaeophyceae) zygote is actin-myosin and secretion dependent.Annals of botany · 2017Article
- Calreticulin is required for calcium homeostasis and proper pollen tube tip growth in Petunia.Planta · 2017Article
- Signaling with Ions: The Keystone for Apical Cell Growth and Morphogenesis in Pollen Tubes.Plant physiology · 2017Review
- The Cytoskeleton and Its Regulation by Calcium and Protons.Plant physiology · 2016Review
- Class XI Myosins Move Specific Organelles in Pollen Tubes and Are Required for Normal Fertility and Pollen Tube Growth in Arabidopsis.Plant physiology · 2015Article
- Navigating the plant cell: intracellular transport logistics in the green kingdom.Molecular biology of the cell · 2015Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant myosin XI functions as a motor that generates cytoplasmic streaming in plant cells. Although cytoplasmic streaming is known to be regulated by intracellular Ca(2+) concentration, the molecular mechanism underlying this control is not fully understood. Here, we investigated the mechanism of regulation of myosin XI by Ca(2+) at the molecular level. Actin filaments were easily detached from myosin XI in an in vitro motility assay at high Ca(2+) concentration (pCa 4) concomitant with the detachment of calmodulin light chains from the neck domains. Electron microscopic observations showed that myosin XI at pCa 4 shortened the neck domain by 30%. Single-molecule analysis revealed that the step size of myosin XI at pCa 4 was shortened to 27 nm under low load and to 22 nm under high load compared with 35 nm independent of the load for intact myosin XI. These results indicate that modulation of the mechanical properties of the neck domain is a key factor for achieving the Ca(2+)-induced regulation of cytoplasmic streaming.
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