Evidence map›Paper›PMID 22740010›Full record

SynthesisCirculation. Cardiovascular quality and outcomes2012

Systematic review and cost-benefit analysis of radial artery access for coronary angiography and intervention.

Matthew D Mitchell, Jaekyoung A Hong, Bruce Y Lee, Craig A Umscheid, Sarah M Bartsch, Creighton W Don

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Circulation. Cardiovascular quality and outcomes, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  4. Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Review
  9. Radial artery access in interventional cardiology: a review of current practices.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2025
    Review
  10. Article
  11. Cost comparison of liquid versus particulate embolic agents for middle meningeal artery embolization in chronic subdural hematoma.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  12. Rate of periprocedural stroke in diagnostic cerebral angiograms comparing transradial versus transfemoral access.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024
    Article
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  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matthew D MitchellCenter for Evidence-based Practice, University of Pennsylvania Health System, Philadelphia, PA, USA. mdmitchell@uphs.upenn.edu
Jaekyoung A Hong
Bruce Y Lee
Craig A Umscheid
Sarah M Bartsch
Creighton W Don

Funding

Training, Outreach & Diversity ComponentU54GM088491 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BROWN, SHAWN T. · 2009 to 2018
$16.7M
Institute for Translational Health Science (KL2)KL2RR025015 · NCRR · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2007 to 2011
$9.3M
NCRR NIH HHS KL2 RR025015NCRR NIH HHS RR025015NIGMS NIH HHS 1U54GM088491-0109NIGMS NIH HHS U54 GM088491
6 · The paper itself

Abstract

backgroundRadial artery access for coronary angiography and interventions has been promoted for reducing hemostasis time and vascular complications compared with femoral access, yet it can take longer to perform and is not always successful, leading to concerns about its cost. We report a cost-benefit analysis of radial catheterization based on results from a systematic review of published randomized controlled trials. METHODS AND

resultsThe systematic review added 5 additional randomized controlled trials to a prior review, for a total of 14 studies. Meta-analyses, following Cochrane procedures, suggested that radial catheterization significantly increased catheterization failure (OR, 4.92; 95% CI, 2.69-8.98), but reduced major complications (OR, 0.32; 95% CI, 0.24-0.42), major bleeding (OR, 0.39; 95% CI, 0.27-0.57), and hematoma (OR, 0.36; 95% CI, 0.27-0.48) compared with femoral catheterization. It added approximately 1.4 minutes to procedure time (95% CI, -0.22 to 2.97) and reduced hemostasis time by approximately 13 minutes (95% CI, -2.30 to -23.90). There were no differences in procedure success rates or major adverse cardiovascular events. A stochastic simulation model of per-case costs took into account procedure and hemostasis time, costs of repeating the catheterization at the alternate site if the first catheterization failed, and the inpatient hospital costs associated with complications from the procedure. Using base-case estimates based on our meta-analysis results, we found the radial approach cost $275 (95% CI, -$374 to -$183) less per patient from the hospital perspective. Radial catheterization was favored over femoral catheterization under all conditions tested.

conclusionsRadial catheterization was favored over femoral catheterization in our cost-benefit analysis.

Indexed as

Hospital CostsRadial ArteryAngioplasty, Balloon, CoronaryCardiac CatheterizationComputer SimulationCoronary AngiographyCost-Benefit AnalysisCost SavingsEvidence-Based MedicineFemoral ArteryHumansModels, EconomicOdds RatioRandomized Controlled Trials as TopicStochastic ProcessesTime Factors

Identifiers

PMID22740010
PMCPMC3430729

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.