ArticleAmerican journal of hypertension2012
Visit-to-visit and ambulatory blood pressure variability as predictors of incident cardiovascular events in patients with hypertension.
Article in American journal of hypertension, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
69 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Blood pressure variability and cardiovascular disease: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2016Pooled it
- Prognostic significance of visit-to-visit systolic blood pressure variability: a meta-analysis of 77,299 patients.Journal of clinical hypertension (Greenwich, Conn.) · 2015Pooled it
- Visit-to-visit variability of blood pressure and cardiovascular disease and all-cause mortality: a systematic review and meta-analysis.Hypertension (Dallas, Tex. : 1979) · 2014Pooled it
- Impact of febuxostat on visit-to-visit blood pressure variability: insights from the randomised PRIZE Study.RMD open · 2022Trial
- Systolic blood pressure variability and lower extremity amputation in a non-elderly population with diabetes.Diabetes research and clinical practice · 2016Trial
- Visit-to-Visit Variability of Blood Pressure and Coronary Heart Disease, Stroke, Heart Failure, and Mortality: A Cohort Study.Annals of internal medicine · 2015Trial
- Visit-to-visit blood pressure variability and cardiovascular death in the Systolic Hypertension in the Elderly Program.Journal of clinical hypertension (Greenwich, Conn.) · 2014Trial
- Relationships between metrics of visit-to-visit variability of blood pressure.Journal of human hypertension · 2013Trial
- Association of BP variability with mortality among African Americans with CKD.Clinical journal of the American Society of Nephrology : CJASN · 2013Trial
- Association Between Visit-to-Visit Mean Arterial Pressure Variability and the Risk of Ischemic Heart Disease and Ischemic Stroke Among Patients With Hypertension in Thailand.Clinical Medicine Insights. Cardiology · 2025Article
- Beyond the beats: exploring the link between blood pressure fluctuations with anxiety, depression, and sleep.Frontiers in psychiatry · 2025Article
- Relationship between visit-to-visit blood pressure variability and depressive mood in Korean primary care patients.BMC primary care · 2024Article
- Importance of anemia in heart failure over blood pressure variability.Clinical cardiology · 2023Article
- Observational
- Determinants of visit-to-visit systolic blood pressure variability among Ghanaians with hypertension and diabetes mellitus.Ghana medical journal · 2023Article
- Home blood pressure monitoring: a position statement from the Korean Society of Hypertension Home Blood Pressure Forum.Clinical hypertension · 2022Review
- Association of Circulating Osteoprotegerin Level with Blood Pressure Variability in Patients with Chronic Kidney Disease.Journal of clinical medicine · 2021Article
- Article
- Visit-to-visit office blood pressure variability combined with Framingham risk score to predict all-cause mortality: A post hoc analysis of the systolic blood pressure intervention trial.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- Association of 1-Year Blood Pressure Variability With Long-term Mortality Among Adults With Coronary Artery Disease: A Post Hoc Analysis of a Randomized Clinical Trial.JAMA network open · 2021Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundVisit-to-visit blood pressure variability (BPV) has been shown to be a prognostic indicator in hypertensive patients. We designed this study to clarify the impacts of clinic and ambulatory BPV in predicting cardiovascular disease (CVD).
methodsWe performed ambulatory BP monitoring (ABPM) in 457 hypertensive patients. Visit-to-visit BPV and ambulatory BPV were calculated as the SDs of clinic BP, awake BP, and sleep BP. The mean age of the subjects was 67.0 ± 9.2 years, and they were followed for 67 ± 26 months. Stroke, myocardial infarction, and sudden cardiac death were defined as Hard CVD events, and these plus angina, heart failure, and other CVDs were defined as All CVD events. Multivariable Cox hazard regression models predicting CVD events were used to estimate the adjusted hazard ratio (HR) and 95% confidence interval (CI) for different measures of BPV with adjustment for significant covariates.
resultsIn multivariable analyses, the BPV of clinic systolic BP (SBP) was an independent predictor for All CVD events (HR, 2.20; 95% CI, 1.25-3.88; P < 0.01), but not for Hard CVD events (P = 0.20). On the other hand, the BPV of sleep SBP was an independent predictor for Hard CVD events (HR, 2.21; 95% CI, 1.08-4.53; P = 0.03), but not for All CVD events (P = 0.88). Diastolic BPV exhibited the same pattern.
conclusionsThese findings suggest that visit-to-visit BPV and ambulatory BPV are separately useful in predicting cardiovascular outcomes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.