ArticleEnvironmental health perspectives2012
Lung cancer and elemental carbon exposure in trucking industry workers.
Article in Environmental health perspectives, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Lack of association between occupational exposure to diesel exhaust and risk of pancreatic cancer: a systematic evaluation of available data.International archives of occupational and environmental health · 2014Pooled it
- Exposure-response estimates for diesel engine exhaust and lung cancer mortality based on data from three occupational cohorts.Environmental health perspectives · 2014Pooled it
- Occupational Exposure to Ambient Air Pollution: At-Risk Worker Groups, Regulatory and Research Needs An Official American Thoracic Society Workshop Report.Annals of the American Thoracic Society · 2025Article
- Lung cancer clusters and air pollution exposure in Wayne County, Michigan: an autoregressive distributed lag model.Journal of thoracic disease · 2025Article
- Disability in mitochondrial aerobic metabolism and MgBMC medicine · 2025Article
- Airborne particulate matter and diesel engine exhaust on infrastructure construction sites in the Copenhagen metropolitan area.Annals of work exposures and health · 2024Article
- Critical Issues in Assessing Occupational Exposure to Diesel Dust Exhaust.La Medicina del lavoro · 2024Article
- Research Recommendations for Selected IARC-Classified Agents: Impact and Lessons Learned.Environmental health perspectives · 2023Review
- Exposure to diesel engine exhaust and alterations to the Cys34/Lys525 adductome of human serum albumin.Environmental toxicology and pharmacology · 2022Article
- Does air pollution contribute to urban-rural disparity in male lung cancer diseases in China?Environmental science and pollution research international · 2022Article
- Epigenetic Regulation in Exposome-Induced Tumorigenesis: Emerging Roles of ncRNAs.Biomolecules · 2022Review
- Elevated urinary mutagenicity among those exposed to bituminous coal combustion emissions or diesel engine exhaust.Environmental and molecular mutagenesis · 2021Article
- Assessment of occupational exposure to diesel particulate matter through evaluation of 1-nitropyrene and 1-aminopyrene in surface coal miners, India.Environmental monitoring and assessment · 2021Article
- Determinants of citation in the literature on diesel exhaust exposure and lung cancer: a citation analysis.BMJ open · 2020Article
- Diesel Engine Exhaust Exposure, Smoking, and Lung Cancer Subtype Risks. A Pooled Exposure-Response Analysis of 14 Case-Control Studies.American journal of respiratory and critical care medicine · 2020Article
- Cancer risk in road transportation workers: a national representative cohort study with 600,000 person-years of follow-up.Scientific reports · 2020Article
- Associations between exposure to ethylene oxide, job termination, and cause-specific mortality risk.American journal of industrial medicine · 2020Article
- Global Epidemiology of Lung Cancer.Annals of global health · 2019Review
- Diesel Exhaust and Lung Cancer-Aftermath of Becoming an IARC Group 1 Carcinogen.American journal of epidemiology · 2018Article
- Effects of FAME biodiesel and HVORD on emissions from an older-technology diesel engine.Mining engineering · 2017Article
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6 authors.
Funding
Abstract
backgroundDiesel exhaust has been considered to be a probable lung carcinogen based on studies of occupationally exposed workers. Efforts to define lung cancer risk in these studies have been limited in part by lack of quantitative exposure estimates.
objectiveWe conducted a retrospective cohort study to assess lung cancer mortality risk among U.S. trucking industry workers. Elemental carbon (EC) was used as a surrogate of exposure to engine exhaust from diesel vehicles, traffic, and loading dock operations.
methodsWork records were available for 31,135 male workers employed in the unionized U.S. trucking industry in 1985. A statistical model based on a national exposure assessment was used to estimate historical work-related exposures to EC. Lung cancer mortality was ascertained through the year 2000, and associations with cumulative and average EC were estimated using proportional hazards models.
resultsDuration of employment was inversely associated with lung cancer risk consistent with a healthy worker survivor effect and a cohort composed of prevalent hires. After adjusting for employment duration, we noted a suggestion of a linear exposure-response relationship. For each 1,000-µg/m³ months of cumulative EC, based on a 5-year exposure lag, the hazard ratio (HR) was 1.07 [95% confidence interval (CI): 0.99, 1.15] with a similar association for a 10-year exposure lag [HR = 1.09 (95% CI: 0.99, 1.20)]. Average exposure was not associated with relative risk.
conclusionsLung cancer mortality in trucking industry workers increased in association with cumulative exposure to EC after adjusting for negative confounding by employment duration.
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