Evidence map›Paper›PMID 22738313›Full record

ArticlePediatric transplantation2013

Isolated unilateral cytomegalovirus retinitis: a rare long-term complication after pediatric liver transplantation.

James E Squires, Robert A Sisk, William F Balistreri, Rohit Kohli

Abstract readCase Reports
In one paragraph

Article in Pediatric transplantation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

James E SquiresPediatric Liver Care Center, Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Robert A Sisk
William F Balistreri
Rohit Kohli

Funding

Role of Ileum in Reducing Obesity Related ComorbiditiesK08DK084310 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI KOHLI, ROHIT · 2009 to 2013
$602k
NIDDK NIH HHS K08 DK084310NIDDK NIH HHS K08 DK084310-01
6 · The paper itself

Abstract

To highlight the rare yet devastating complication of CMV retinitis in a minimally immunosuppressed patient eight yr after liver transplantation for biliary atresia. A 22-yr-old female status-post deceased donor liver transplant at age 13 secondary to biliary atresia receiving single agent immunosuppression presented with acute, unilateral, profound decrease in visual acuity. The patient was diagnosed to have acute onset unilateral CMV retinitis. Retinal examination uncovered classical appearance of retinal whitening and retinal hemorrhages with extensive macular involvement. CMV retinitis can occur as a late complication following liver transplantation. Additionally, CMV retinal disease can occur in the absence of laboratory evidence of CMV infection and independent of additional clinical features suggesting CMV disease. Currently, there is no standard of care regarding screening for CMV retinitis, and thus, further research is needed to define the need for potential changes in current clinical practices and post-transplant screening protocols.

Indexed as

Biliary AtresiaCytomegalovirusCytomegalovirus RetinitisFemaleGanciclovirHumansImmunosuppressive AgentsLiver FailureLiver TransplantationTime FactorsVision, OcularYoung AdultGanciclovirImmunosuppressive Agents

Identifiers

PMID22738313
PMCPMC3461246

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.