Evidence map›Paper›PMID 22737559›Full record

ArticleIranian Red Crescent medical journal2012

Comparing the Effect of Phenytoin Syrup and Triamcinolone Acetonide Ointment on Aphthous Ulcers in Patients with Behcet's Syndrome.

M M Fani, H Ebrahimi, S Pourshahidi, E Aflaki, S Shafiee Sarvestani

Open access · greenAbstract read
In one paragraph

Article in Iranian Red Crescent medical journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Interventions for the management of oral ulcers in Behçet's disease.The Cochrane database of systematic reviews · 2014
    Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. A Changed Man: A Rare Case of Behcet's Disease Autoimmune Encephalitis.Journal of community hospital internal medicine perspectives · 2024
    Article
  6. Article
  7. Review
  8. Review
  9. Behçet Disease: An Update for Dermatologists.American journal of clinical dermatology · 2021
    Review
  10. Experimental Therapeutic Solutions for Behcet's Disease.Journal of experimental pharmacology · 2021
    Review
  11. Review
  12. Article
  13. Penicillin in oral aphthosis, new insight for an old drug: A randomized, double-blind, controlled clinical trial.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2020
    Article
  14. Review
  15. Article
  16. Article
  17. The treatment of chronic recurrent oral aphthous ulcers.Deutsches Arzteblatt international · 2014
    Review
  18. [Clinical aspects and treatment of recurrent aphthous ulcers].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

M M FaniDepartment of Oral Medicine, Dental School, Shiraz University of Medical Sciences, Shiraz, Iran.
H Ebrahimi
S Pourshahidi
E Aflaki
S Shafiee Sarvestani
Shiraz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecurrent aphthous stomatitis (RAS) appears to be the most common type of oral ulcers. The lesion is usually self limited but its painful presentation results in some difficulties. Therefore, an efficient therapeutic strategy is required and currently existing therapies seem to be inadequate because of its unclear etiology. Here the therapeutic effect of triamcinolone acetonide ointment as a relatively expensive medication has been compared with phenytoin syrup on aphthous ulcers in patients with Behcet's syndrome.

methodsThirty out of 60 our patients with Behcet's syndrome were randomly treated by phenytoin syrup and the remaining were advised to use 0.1% triamcinolone acetonide ointment. After a week, they were visited again to determine the status of aphthous ulcers.

resultPositive response in the triamcinolone acetonide group and phenytoin group was 86.7% and 53.3%, respectively.

conclusionThe effectiveness of triamcinolone acetonide ointment was more than phenytoin on aphthous ulcers in patients with Behcet's syndrome.

Indexed as

Aphthous ulcerBehcet’s syndromePhenytoinTriamcinolone Acetonide

Identifiers

PMID22737559
PMCPMC3372045
OpenAlexW2108957629

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.