Evidence map›Paper›PMID 22736777›Full record

ArticleBMJ case reports2012

Protein-losing gastropathy associated with cytomegalovirus infection in a child.

Tânia Russo, Claudia Costa, Conceição Crujo, Ana Isabel Lopes

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Pediatric Ménétrier's Disease Triggered byCase reports in pediatrics · 2025
    Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Tânia RussoDepartment of Pediatrics, Hospital de Santo André, EPE, Centro Hospitalar Leiria-Pombal, Leiria, Portugal. tania.russo@gmail.com
Claudia Costa
Conceição Crujo
Ana Isabel Lopes
Hospital de Santa Maria · PTInstituto Politécnico de Leiria · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein-losing gastropathy is a rare entity. Unlike the disease in adults, it usually is benign and self-limited in children. The aetiological contribution of cytomegalovirus has been insufficiently documented and the immunological status of patients was rarely described in most reports. The authors report an 11-year-old boy with generalised oedema and hypoproteinemia. Upper endoscopy with biopsies showed marked hypertrophy of gastric folds and foveolar hyperplasia involving the body and fundus. The presence of cytomegalovirus in gastric tissue was well documented through identification of intranuclear inclusions, immunohistochemistry and PCR. Immunodeficiency was clearly ruled out. Protein-losing gastropathy should be considered in children with oedema and hypoproteinemia. The aetiological diagnosis should be confirmed by endoscopy-based methods.

Indexed as

ChildCytomegalovirusCytomegalovirus InfectionsEdemaHumansHypertrophyHypoproteinemiaMaleProtein-Losing EnteropathiesStomachStomach DiseasesUltrasonography

Identifiers

PMID22736777
PMCPMC3448344
OpenAlexW2060295012

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.