Evidence map›Paper›PMID 22735495›Full record

Trial reportContemporary clinical trials2012

Asthma randomized trial of indoor wood smoke (ARTIS): rationale and methods.

Curtis W Noonan, Tony J Ward

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Contemporary clinical trials, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Trial
  2. Efficacy of interventions targeting household air pollution from residential wood stoves.Journal of exposure science & environmental epidemiology · 2017
    Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Indoor Air Pollution and Respiratory Health.Clinics in chest medicine · 2020
    Review
  8. Article
  9. Article
  10. Article
  11. Dietary intake is associated with respiratory health outcomes and DNA methylation in children with asthma.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2017
    Article
  12. Dust Allergens within Rural Northern Rocky Mountain Residences.Jacobs journal of allergy and immunology · 2015
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Curtis W NoonanCenter for Environmental Health Sciences, Department of Biomedical Sciences, The University of Montana, Missoula, MT 59812, USA. curtis.noonan@umontana.edu
Tony J Ward
Center for Environmental Health · USUniversity of Montana · US

Funding

THE ROLE OF PULMONARY SUBPOPULATIONS AND TH2 IMMUNITY IN BALB/C SILICOSIS MODELP20RR017670 · NCRR · UNIVERSITY OF MONTANA · PI ROBERTS, KEVAN · 2002 to 2011
$22.0M
Molecular Histology and Fluorescent ImagingP30GM103338 · NIGMS · UNIVERSITY OF MONTANA · PI HOLIAN, ANDRIJ · 2013 to 2017
$5.6M
Wood stove interventions and child respiratory infections in rural communitiesR01ES022649 · NIEHS · UNIVERSITY OF MONTANA · PI NOONAN, CURTIS WILLIAM, WARD, TONY JOHN · 2014 to 2018
$2.7M
Residential Wood Smoke Interventions Improving Health in Native American PopulationsR01ES022583 · NIEHS · UNIVERSITY OF MONTANA · PI BELCOURT, ANNIE ELISE, NOONAN, CURTIS WILLIAM · 2014 to 2019
$2.4M
Indoor woodsmoke PM and asthma: a randomized trialR01ES016336 · NIEHS · UNIVERSITY OF MONTANA · PI NOONAN, CURTIS WILLIAM, WARD, TONY JOHN · 2008 to 2012
$2.0M
NCRR NIH HHS P20 RR017670NIEHS NIH HHS 1R01ES016336-01NIEHS NIH HHS 3R01ES016336-02S1NIEHS NIH HHS R01 ES016336NIEHS NIH HHS R01 ES022583NIEHS NIH HHS R01 ES022649NIGMS NIH HHS P30 GM103338
6 · The paper itself

Abstract

backgroundParticulate matter (PM) exposures have been linked with poor respiratory health outcomes, especially among susceptible populations such as asthmatic children. Smoke from biomass combustion for residential home heating is an important source of PM in many rural or peri-urban areas in the United States.

aimTo assess the efficacy of residential interventions that reduce indoor PM exposure from wood stoves and to quantify the corresponding improvements in quality of life and health outcomes for asthmatic children.

designThe asthma randomized trial of indoor wood smoke (ARTIS) study is an in-home intervention study of susceptible children exposed to biomass combustion smoke. Children, ages 7 to 17, with persistent asthma and living in homes that heat with wood stoves were recruited for this three arm randomized placebo-controlled trial. Two household-level intervention strategies, wood stove replacement and air filters, were compared to a sham air filter placebo. Improvement in quality of life of asthmatic children was the primary outcome. Secondary asthma-related health outcomes included peak expiratory flow (PEF) and forced expiratory volume in first second (FEV(1)), biomarkers in exhaled breath condensate, and frequency of asthma symptoms, medication usage, and healthcare utilization. Exposure outcomes included indoor and outdoor PM(2.5) mass, particle counts of several size fractions, and carbon monoxide. DISCUSSION: To our knowledge, this was the first randomized trial in the US to utilize interventions targeting residential wood stoves to assess the impact on indoor PM and health outcomes in a susceptible population.

Indexed as

WoodAdolescentAir FiltersAir Pollution, IndoorAsthmaBiomarkersChildEnvironmental MonitoringFemaleFiltrationHumansMaleMulticenter Studies as TopicParticulate MatterQuality of LifeRandomized Controlled Trials as TopicBiomarkersParticulate MatterSmoke

Identifiers

PMID22735495
PMCPMC3408844
OpenAlexW2046984139

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.