Trial reportBMJ (Clinical research ed.)2012
Effectiveness of home based early intervention on children's BMI at age 2: randomised controlled trial.
Trial report in BMJ (Clinical research ed.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06773299 (ENhancing Intergenerational HeAlth in Nigeria), which is not on this map. Cited by 147 papers, 31 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
ENhancing Intergenerational HeAlth in Nigeria: Peripartum as Critical Life StagE for CardioVascular Health
Who cites it
147 citing papers in PubMed, 31 syntheses or guidelines pooled it, 327 citations in OpenAlex.
- Interventions to Reduce Screen Time in Preschool-Aged Children: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Pooled it
- Precision Health Approaches in Primary Childhood Obesity Prevention: A Systematic Review of Tailored and Risk-Based Interventions.Pediatric obesity · 2026Pooled it
- Parent-focused behavioural interventions for the prevention of early childhood obesity (TOPCHILD): a systematic review and individual participant data meta-analysis.Lancet (London, England) · 2025Pooled it
- Pooled it
- Effects of Exclusive Breastfeeding Promotion Interventions on Child Outcomes: A Systematic Review and Meta-Analysis.Annals of nutrition & metabolism · 2024Pooled it
- The effectiveness of interventions during the first 1,000 days to improve energy balance-related behaviors or prevent overweight/obesity in children from socio-economically disadvantaged families of high-income countries: a systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023Pooled it
- Family-centred interventions for Indigenous early childhood well-being by primary healthcare services.The Cochrane database of systematic reviews · 2022Pooled it
- Support for healthy breastfeeding mothers with healthy term babies.The Cochrane database of systematic reviews · 2022Pooled it
- Determinants of rapid infant weight gain: A pooled analysis of seven cohorts.Pediatric obesity · 2022Pooled it
- Home- and Community-Based Interventions for Physical Activity and Early Child Development: A Systematic Review of Effective Strategies.International journal of environmental research and public health · 2022Pooled it
- Examining the sustainability of effects of early childhood obesity prevention interventions: Follow-up of the EPOCH individual participant data prospective meta-analysis.Pediatric obesity · 2022Pooled it
- The effectiveness of nurse-led interventions to prevent childhood and adolescent overweight and obesity: A systematic review of randomised trials.Journal of advanced nursing · 2021Pooled it
- Measurement of screen time among young children aged 0-6 years: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021Pooled it
- Addressing obesity in the first 1000 days in high risk infants: Systematic review.Maternal & child nutrition · 2021Pooled it
- Interventions that prevent or reduce obesity in children from birth to five years of age: A systematic review.Journal of child health care : for professionals working with children in the hospital and community · 2021Pooled it
- Pooled it
- Content and Quality of Infant Feeding Smartphone Apps: Five-Year Update on a Systematic Search and Evaluation.JMIR mHealth and uHealth · 2020Pooled it
- Interventions for increasing fruit and vegetable consumption in children aged five years and under.The Cochrane database of systematic reviews · 2020Pooled it
- Interventions for increasing fruit and vegetable consumption in children aged five years and under.The Cochrane database of systematic reviews · 2019Pooled it
- Interventions for preventing obesity in children.The Cochrane database of systematic reviews · 2019Pooled it
87 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the effectiveness of a home based early intervention on children's body mass index (BMI) at age 2.
designRandomised controlled trial.
settingThe Healthy Beginnings Trial was conducted in socially and economically disadvantaged areas of Sydney, Australia, during 2007-10.
participants667 first time mothers and their infants.
interventionEight home visits from specially trained community nurses delivering a staged home based intervention, one in the antenatal period, and seven at 1, 3, 5, 9, 12, 18 and 24 months after birth. Timing of the visits was designed to coincide with early childhood developmental milestones.
main outcome measuresThe primary outcome was children's BMI (the healthy BMI ranges for children aged 2 are 14.12-18.41 for boys and 13.90-18.02 for girls). Secondary outcomes included infant feeding practices and TV viewing time when children were aged 2, according to a modified research protocol. The data collectors and data entry staff were blinded to treatment allocation, but the participating mothers were not blinded.
results497 mothers and their children (75%) completed the trial. An intention to treat analysis in all 667 participants recruited, and multiple imputation of BMI for the 170 lost to follow-up and the 14 missing, showed that mean BMI was significantly lower in the intervention group (16.53) than in the control group (16.82), with a difference of 0.29 (95% confidence interval -0.55 to -0.02; P=0.04).
conclusionsThe home based early intervention delivered by trained community nurses was effective in reducing mean BMI for children at age 2.
trial registrationAustralian Clinical Trial Registry No 12607000168459.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.