Evidence map›Paper›PMID 22734811›Full record

ReviewJournal of immunotoxicology

Immunotoxicology of arc welding fume: worker and experimental animal studies.

Patti C Zeidler-Erdely, Aaron Erdely, James M Antonini

Abstract readReview
In one paragraph

Review in Journal of immunotoxicology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Welder's Anthrax Treated with Obiltoxaximab - Louisiana, 2024.MMWR. Morbidity and mortality weekly report · 2026
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  19. Acute respiratory effects and biomarkers of inflammation due to welding-derived nanoparticle aggregates.International archives of occupational and environmental health · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Patti C Zeidler-ErdelyPathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA.
Aaron Erdely
James M Antonini

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Arc welding processes generate complex aerosols composed of potentially hazardous metal fumes and gases. Millions of workers worldwide are exposed to welding aerosols daily. A health effect of welding that is of concern to the occupational health community is the development of immune system dysfunction. Increased severity, frequency, and duration of upper and lower respiratory tract infections have been reported among welders. Specifically, multiple studies have observed an excess mortality from pneumonia in welders and workers exposed to metal fumes. Although several welder cohort and experimental animal studies investigating the adverse effects of welding fume exposure on immune function have been performed, the potential mechanisms responsible for these effects are limited. The objective of this report was to review both human and animal studies that have examined the effect of welding fume pulmonary exposure on local and systemic immune responses.

Indexed as

WeldingAerosolsAir Pollutants, OccupationalAnimalsHazardous SubstancesHumansImmune System DiseasesLungMetalsModels, AnimalOccupational ExposurePneumoniaSmokeAerosolsAir Pollutants, OccupationalHazardous SubstancesMetalsSmoke

Identifiers

PMID22734811
PMCPMC4696487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.