ArticleBMC infectious diseases2012
Predictors of human papillomavirus infection in women undergoing routine cervical cancer screening in Spain: the CLEOPATRE study.
Article in BMC infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association between male circumcision and women's biomedical health outcomes: a systematic review.The Lancet. Global health · 2017Pooled it
- The impact of smoking on HPV infection and the development of anogenital warts.International journal of colorectal disease · 2014Pooled it
- Rural-urban and educational gradients in head and neck cancer incidence in Finland from 1977 to 2021.Acta oncologica (Stockholm, Sweden) · 2025Article
- Article
- Population-based age- and type-specific prevalence of human papillomavirus among non-vaccinated women aged 30 years and above in Germany.BMC infectious diseases · 2024Article
- Prevalence and genotype distribution of potential high-risk and high-risk human papillomavirus among women attending selected reproductive health clinics in lake victoria basin-kenya: a cross-sectional study.BMC women's health · 2024Article
- Evidence-based circumcision policy for Australia.Journal of men's health · 2022Article
- Article
- Article
- Does Male Circumcision Reduce Women's Risk of Sexually Transmitted Infections, Cervical Cancer, and Associated Conditions?Frontiers in public health · 2019Article
- Article
- [Sexual risk behaviours and PAP testing in university women vaccinated against human papillomavirus].Atencion primaria · 2018Article
- Population-based prevalence of cervical infection with human papillomavirus genotypes 16 and 18 and other high risk types in Tlaxcala, Mexico.BMC infectious diseases · 2016Article
- Risk of cervical HPV infection and prevalence of vaccine-type and other high-risk HPV types among sexually active teens and young women (13-26 years) enrolled in the VALHIDATE study.Human vaccines & immunotherapeutics · 2014Article
- PrediQt-Cx: post treatment health related quality of life prediction model for cervical cancer patients.PloS one · 2014Article
- Condom use and human papillomavirus in men.The Journal of infectious diseases · 2013Article
- Should male circumcision be advocated for genital cancer prevention?Asian Pacific journal of cancer prevention : APJCP · 2012Article
- [Prevalence of non-vaccinable high risk genotypes of human papillomavirus in the Early Detection of Cervical Cancer Program in Cantabria].Atencion primariaArticle
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Authors and funding
14 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundHuman papillomavirus (HPV) is a sexually transmitted infection that may lead to development of precancerous and cancerous lesions of the cervix. The aim of the current study was to investigate socio-demographic, lifestyle, and medical factors for potential associations with cervical HPV infection in women undergoing cervical cancer screening in Spain.
methodsThe CLEOPATRE Spain study enrolled 3 261 women aged 18-65 years attending cervical cancer screening across the 17 Autonomous Communities. Liquid-based cervical samples underwent cytological examination and HPV testing. HPV positivity was determined using the Hybrid Capture II assay, and HPV genotyping was conducted using the INNO-LiPA HPV Genotyping Extra assay. Multivariate logistic regression was used to identify putative risk factors for HPV infection.
resultsA lifetime number of two or more sexual partners, young age (18-25 years), a history of genital warts, and unmarried status were the strongest independent risk factors for HPV infection of any type. Living in an urban community, country of birth other than Spain, low level of education, and current smoking status were also independent risk factors for HPV infection. A weak inverse association between condom use and HPV infection was observed. Unlike monogamous women, women with two or more lifetime sexual partners showed a lower risk of infection if their current partner was circumcised (P for interaction, 0.005) and a higher risk of infection if they were current smokers (P for interaction, 0.01).
conclusionThis is the first large-scale, country-wide study exploring risk factors for cervical HPV infection in Spain. The data strongly indicate that variables related to sexual behavior are the main risk factors for HPV infection. In addition, in non-monogamous women, circumcision of the partner is associated with a reduced risk and smoking with an increased risk of HPV infection.
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