ReviewNature reviews. Clinical oncology2012
Breast cancer in young women.
Review in Nature reviews. Clinical oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
96 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comprehensive Review of Breast Cancer Consequences for the Patients and Their Coping Strategies: A Systematic Review.Cancer control : journal of the Moffitt Cancer CenterPooled it
- Breast Cancer Liver Metastasis: Primary tumor predictors and histopathologic characteristics of metastatic lesions.Research square · 2026Article
- Associations of Age With Tumor Genomic Characteristics in Relapsed/Refractory Cancers Interrogated With the NCI-MATCH Trial Targeted Gene Panel Assay.JCO precision oncology · 2026Article
- PREDICT v3.0 outperforms v2.2 in young (25-40 years) breast cancer patients according to real-world data from a large Swedish population-based registry.Breast cancer research : BCR · 2026Article
- An international cohort study of breast cancer survival in young women.BJC reports · 2026Article
- Exome-Wide Association Analysis Identifies Rare Germline Susceptibility Variants in Early-Onset Breast Cancer Among Saudi Women.International journal of molecular sciences · 2026Article
- Adherence to oral endocrine therapy by menopausal status: post hoc insights from a remote monitoring randomized trial.NPJ breast cancer · 2026Article
- Validation of PREDICT tool v2.2 in patients with early-stage breast cancer enrolled in the GIM and MIG trials.ESMO open · 2026Article
- Clinical-pathological patterns and prognosis of young women with breast cancer brain metastases: a single-center retrospective study.Journal of neuro-oncology · 2025Article
- MGAT4EP promotes tumor progression and serves as a prognostic marker for breast cancer.Cancer biology & therapy · 2025Article
- Global, Regional, and National Burden of Breast Cancer in Adolescents and Young Adults Aged 15-39 Years From 1990 to 2021 Based on the Global Burden of Disease Study 2021.Cancer innovation · 2025Article
- Hospital and community supportive care for young women with breast cancer: a scoping review and environmental scan.Journal of cancer survivorship : research and practice · 2025Review
- Evaluating PREDICT and developing outcome prediction models in early-onset breast cancer using data from Alberta, Canada.Breast cancer research and treatment · 2025Article
- Analysis the Burden of Breast Cancer Among Adolescents and Young Adults Using the Global Burden of Disease 2021.Annals of surgical oncology · 2025Article
- Sociodemographic characteristics and health status of women with breast cancer and COVID 19 diagnosis by menopausal status a cross sectional study.Scientific reports · 2025Article
- Pathway to care among adolescents and young adults with breast cancer in Nigeria: a mixed methods study.BMC cancer · 2025Article
- Novel models by machine learning to predict the risk of cardiac disease-specific death in young patients with breast cancer.Discover oncology · 2024Article
- Tumour biology and survival outcomes in young women with breast cancer: single-centre retrospective analysis.BJS open · 2024Article
- Rare Germline Variants in DNA Repair Genes Detected inCancers · 2024Article
- Risk of first recurrence after treatment in a population-based cohort of young women with breast cancer.Breast cancer research and treatment · 2024Article
36 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
About one in 300 women will be diagnosed with breast cancer before the age of 40. Advances in screening have not had an impact on mortality in women who are too young to be candidates for screening. Risk factors for early breast cancer include a lean body habitus and recent use of an oral contraceptive. Breast cancers in very young women are typically aggressive, in part owing to the over-representation of high-grade, triple-negative tumours, but young age is an independent negative predictor of cancer-specific survival. Very early age-of-onset also correlates strongly with the risk of local recurrence and with the odds of contralateral breast cancer. Given the high risks of local and distant recurrence in young women with invasive breast cancer, most (if not all) young patients are candidates for chemotherapy. It is hoped that by increasing breast cancer awareness, the proportion of invasive breast cancers that are diagnosed at 2.0 cm or smaller will increase and that this will lead to a reduction in mortality.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.