Evidence map›Paper›PMID 22733210›Full record

SynthesisArchives of internal medicine2012

Hospital-based medication reconciliation practices: a systematic review.

Stephanie K Mueller, Kelly Cunningham Sponsler, Sunil Kripalani, Jeffrey L Schnipper

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Archives of internal medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 227 papers, 19 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
227citing papers in PubMed, 19 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

227 citing papers in PubMed, 19 syntheses or guidelines pooled it.

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  3. Clinical and economic impact of medication reconciliation in cancer patients: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
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  5. Effect of medication reconciliation interventions on outcomes: A systematic overview of systematic reviews.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2019
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  7. Impact of medication reconciliation for improving transitions of care.The Cochrane database of systematic reviews · 2018
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  14. Electronic tools to support medication reconciliation: a systematic review.Journal of the American Medical Informatics Association : JAMIA · 2017
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167 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Stephanie K MuellerBrigham and Women's Hospital Hospitalist Service and Division of General Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Kelly Cunningham Sponsler
Sunil Kripalani
Jeffrey L Schnipper

Funding

Pharmacist Intervention for Low Literacy in Cardiovascular Disease (PILL-CVD)R01HL089755 · NHLBI · VANDERBILT UNIVERSITY · PI KRIPALANI, SUNIL · 2007 to 2009
$1.8M
Multi-Center Medication Reconciliation Quality Improvement Study - MARQUISR18HS019598 · AHRQ · SOCIETY OF HOSPITAL MEDICINE · PI SCHNIPPER, JEFFREY LAWRENCE · 2010 to 2012
$1.5M
AHRQ HHS 1 R18 HS019598-01AHRQ HHS R18 HS019598NHLBI NIH HHS R01 HL089755PHS HHS T32-HP10251
6 · The paper itself

Abstract

backgroundMedication discrepancies at care transitions are common and lead to patient harm. Medication reconciliation is a strategy to reduce this risk.

objectivesTo summarize available evidence on medication reconciliation interventions in the hospital setting and to identify the most effective practices. DATA SOURCES: MEDLINE (1966 through February 2012) and a manual search of article bibliographies. STUDY SELECTION: Twenty-six controlled studies. DATA EXTRACTION: Data were extracted on study design, setting, participants, inclusion/exclusion criteria, intervention components, timing, comparison group, outcome measures, and results. DATA SYNTHESIS: Studies were grouped by type of medication reconciliation intervention-pharmacist related, information technology (IT), or other-and were assigned quality ratings using US Preventive Services Task Force criteria.

resultsFifteen of 26 studies reported pharmacist-related interventions, 6 evaluated IT interventions, and 5 studied other interventions. Six studies were classified as good quality. The comparison group for all the studies was usual care; no studies compared different types of interventions. Studies consistently demonstrated a reduction in medication discrepancies (17 of 17 studies), potential adverse drug events (5 of 6 studies), and adverse drug events (2 of 2 studies) but showed an inconsistent reduction in postdischarge health care utilization (improvement in 2 of 8 studies). Key aspects of successful interventions included intensive pharmacy staff involvement and targeting the intervention to a high-risk patient population.

conclusionsRigorously designed studies comparing different inpatient medication reconciliation practices and their effects on clinical outcomes are scarce. Available evidence supports medication reconciliation interventions that heavily use pharmacy staff and focus on patients at high risk for adverse events. Higher-quality studies are needed to determine the most effective approaches to inpatient medication reconciliation.

Indexed as

Medication ReconciliationDrug-Related Side Effects and Adverse ReactionsHumans

Identifiers

PMID22733210
PMCPMC3575731

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.