ArticlePediatrics2012
Trends in antibiotic use in Massachusetts children, 2000-2009.
Article in Pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Trends in Pediatric Primary Care Visits Among Commercially Insured US Children, 2008-2016.JAMA pediatrics · 2020Article
- Trends in Outpatient Antibiotic Use in 3 Health Plans.Pediatrics · 2019Article
- Vaccination can drive an increase in frequencies of antibiotic resistance among nonvaccine serotypes ofProceedings of the National Academy of Sciences of the United States of America · 2018Article
- Antibiotic Use in Febrile Children Presenting to the Emergency Department: A Systematic Review.Frontiers in pediatrics · 2018Article
- Article
- Parental acceptability of the watchful waiting approach in pediatric acute otitis media.World journal of clinical pediatrics · 2016Article
- Prevalence of Parental Misconceptions About Antibiotic Use.Pediatrics · 2015Article
- Guideline-concordant antibiotic prescribing for pediatric outpatients with otitis media, community-acquired pneumonia, and skin and soft tissue infections in a large multispecialty healthcare system.Clinical research in infectious diseases · 2015Article
- Recent trends in outpatient antibiotic use in children.Pediatrics · 2014Article
- Parents' experiences with pediatric care at retail clinics.JAMA pediatrics · 2013Article
- Population genomics of post-vaccine changes in pneumococcal epidemiology.Nature genetics · 2013Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectiveAntibiotic use rates have declined dramatically since the 1990s. We aimed to determine if, when, and at what level the decline in antibiotic-dispensing rates ended and which diagnoses contributed to the trends.
methodsAntibiotic dispensings and diagnoses were obtained from 2 health insurers for 3- to <72-month-olds in 16 Massachusetts communities from 2000 to 2009. Population-based antibiotic-dispensing rates per person-year (p-y) were determined according to year (September-August) for 3 age groups. Fit statistics were used to identify the most likely year for a change in trend. Rates for the first and last years were compared according to antibiotic category and associated diagnosis.
resultsFrom 2000-2001 to 2008-2009, the antibiotic-dispensing rate for 3- to <24-month-olds decreased 24% (2.3-1.8 antibiotic dispensings per p-y); for 24- to <48-month-olds, it decreased 18% (1.6-1.3 antibiotic dispensings per p-y); and for 48- to <72-month-olds, it decreased 20% (1.4-1.1 antibiotic dispensings per p-y). For 3- to <48-month-olds, rates declined until 2004-2005 and remained stable thereafter; the downward trend for 48- to <72-month-olds ended earlier in 2001-2002. Among 3- to <24-month-olds, first-line penicillin use declined 26%. For otitis media, the dispensing rate decreased 14% and the diagnosis rate declined 9%, whereas the treatment fraction was stable at 63%.
conclusionsThe downward trend in antibiotic dispensings to young children in these communities ended by 2004-2005. This trend was driven by a declining otitis media diagnosis rate. Continued monitoring of population-based dispensing rates will support efforts to avoid returning to previous levels of antibiotic overuse.
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