Evidence map›Paper›PMID 22730865›Full record

ArticleThe journal of extra-corporeal technology2012

BioGlue in 2011: what is its role in cardiac surgery?

Castigliano M Bhamidipati, Joseph S Coselli, Scott A LeMaire

Registry-linked trialAbstract read
In one paragraph

Article in The journal of extra-corporeal technology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03917862 (The Hemostatic Potential of TDM-621 on Ascending Aortic Surgery), which is not on this map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03917862 phase2 / phase3unknown statusnot on this mapstarted 2018, after this paper: background citation

The Hemostatic Potential of TDM-621 on Ascending Aortic Surgery

TypeinterventionalSponsorUniversity of Sao Paulo General HospitalRan2018 to 2020Enrolled200ConditionsAscending Aorta Abnormality, Ascending Aortic Dissection, Ascending Aorta AneurysmArmsTDM-621
3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Inflammatory response induction as a result of BioGlue adhesive application in cardiac surgery - a review of the literature.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2024
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Castigliano M BhamidipatiDepartment of Surgery, State University of New York Upstate Medical University, Syracuse, New York, USA.
Joseph S Coselli
Scott A LeMaire

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BioGlue surgical adhesive was developed as an adjunct for achieving hemostasis during cardiovascular surgery, and it was approved for use in the United States by the Food and Drug Administration in 2001. When applied to cardiovascular tissues, the glutaraldehyde and bovine serum albumin that comprise BioGlue produce strong crosslinking that bonds tissues and seals defects. These features have made BioGlue particularly well suited for preventing bleeding from fragile cardiovascular anastomoses such as those inherent in the repair of acute aortic dissection. Over the 10-year period since its approval, several studies and clinical reports have illuminated the relative risks and benefits of using BioGlue during cardiovascular operations. Understanding these merits and limitations of BioGlue is essential to ensuring its safe and effective use.

Indexed as

Cardiovascular DiseasesCardiovascular Surgical ProceduresHemorrhageHemostasis, SurgicalHumansProteinsBio-glueProteins

Identifiers

PMID22730865
PMCPMC4557450

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.